All CLM-9 reagents are produced in house and quality controlled, including 5 CLM-9 Antibody, 26 CLM-9 Gene, 1 CLM-9 IPKit, 4 CLM-9 Lysate, 4 CLM-9 Protein, 2 CLM-9 qPCR. All CLM-9 reagents are ready to use.
Recombinant CLM-9 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc, C-cleavage.
CLM-9antibodies are validated with different applications, which are ELISA, WB, IP.
CLM-9cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CLM-9 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.