CLEC4D Protein

C-type lectin domain family 4, member D

CLEC4D Products

CLEC4D Protein, Recombinant

Molecule	Species	Description	Cat. No
CLEC4D/CLECSF8	Human	CLEC4D/CLECSF8 Protein, Recombinant	11485-H07H

CLEC4D cDNA Clone

Molecule	Species	Description	Cat. No
CLEC4D/CLECSF8	Human	Homo sapiens CLEC4D/CLECSF8 cDNA Clone	HG11485-M
CLEC4D/CLECSF8	Mouse	Mouse CLEC4D/CLECSF8 cDNA Clone / ORF Clone	MG50946-G
CLEC4D/CLECSF8	Rat	Rat CLEC4D/CLECSF8 cDNA Clone / ORF Clone	RG80213-G

CLEC4D Related Areas

Immunology>>Adhesion Molecule>>Lectin>>CLEC4D/CLECSF8

CLEC4D Alternative Names

CLEC4D, CLECSF8, CLEC-6, CLEC6, MCL, MGC40078, MPCL [Homo sapiens]

Clec4d, Clecsf8, MGC117678, Mpcl, mcl [Mus musculus]

CLEC4D Background

C-type lectin (CLEC) family is a type of carbohydrate-binding protein domain named lectin. C-type lectins are the most diverse and prevalent lectin family in immunity with its requirement for calcium for binding. Proteins including a C-type lectin domain have diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. There are at least 14 types of C-type lectins: typeⅠto typeⅩⅣ. CLEC4D(CLECSF8) is a typeⅡ membrane glycoprotein belonging to the C-type lectin family, with restricted expression in the monocyte/macrophage lineage. It plays important roles in the function of macrophages.

CLEC4D Related Studies

1. Johnson KD, et al. (2007) Friend of GATA-1-independent Transcriptional Repression: A Novel Mode of GATA-1 Function. Blood. 109 (12): 5230-3.
2. Arce I, et al. (2004) The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor.  Eur J Immunol. 34 (1): 210-20.
3. Marshall AS, et al. (2006) Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation. Eur J Immunol. 36 (8): 2159-69.