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CLDN11 / Claudin-11

CLDN11 / Claudin-11 Protein & Antibody

Entrez Gene Summary for CLDN11 / Claudin-11


This CLDN11 gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this CLDN11 gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Aug 2010]

OMIM-Description for CLDN11 / Claudin-11


Bronstein et al. (1996) isolated a novel oligodendrocyte-specific protein in the mouse. The predicted amino acid sequence and structure of the gene product suggested that the protein, which they symbolized Osp, is the central nervous system (CNS) homolog of peripheral myelin protein-22 (601097).

.zh=CLDN11 / Claudin-11


Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. It belongs to the group of claudins.

CLDN11 / Claudin-11 Alternative Names

OSP,OTM, [homo-sapiens]
claudin-11,oligodendrocyte transmembrane protein,oligodendrocyte-specific protein,OSP,OTM, [human]
Claudin11,Claudin-11,oligodendrocyte transmembrane protein,oligodendrocyte-specific protein,Osp,Otm, [mouse]
Osp,Otm,Claudin11,Claudin-11, [mus-musculus]

CLDN11 / Claudin-11 Related Products

CLDN11 / Claudin-11 Proteins

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Human CLDN11 / Claudin-11 Protein (Fc Tag)

CLDN11 / Claudin-11 Antibodies

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CLDN11 / Claudin-11 cDNA Clones

Product nameProduct name
Mouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-Myc tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-Flag tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-OFPSpark tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-Myc tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-OFPSpark tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-OFPSpark tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone in cloning vectorMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-His tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmidRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-Flag tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-Myc tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmidMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-GFPSpark tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-HA tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-His tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-Myc tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-His tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-HA tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-Flag tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-Flag tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-HA tagMouse CLDN11 / Claudin-11 Gene ORF cDNA clone in cloning vectorRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, C-HA tagRat CLDN11 / Claudin-11 Gene ORF cDNA clone expression plasmid, N-His tag

CLDN11 / Claudin-11 ELISA

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