Text Size:AAA

CKM / CK-MM Protein, Antibody, ELISA Kit, cDNA Clone

CKM / CK-MM Related Areas

CKM / CK-MM Related Pathways

CKM / CK-MM Related Product

    CKM / CK-MM Summary & Protein Information

    CKM / CK-MM Background

    Catalytic activity: ATP + creatine = ADP + phosphocreatine.
    Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
    Subcellular location: Cytoplasm.
    Sequence similarity: Belongs to the ATP:guanido phosphotransferase family.
    Contains 1 phosphagen kinase C-terminal domain.
    Contains 1 phosphagen kinase N-terminal domain.
    General information above from UniProt

    CKM, also known as CK-MM, is mainly expressed in skeletal muscle. As the primary CK isoenzyme, it also can be detected in heart muscle. CKM is a subunit of creatine kinase (CK). CK is an enzyme expressed by various tissues and cell types. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). In the cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type).

    CKM / CK-MM Alternative Name

    creatine kinase, muscle,CKM,CKMM,M-CK,creatine kinase M chain,creatine kinase M-type, [human]
    creatine kinase, muscle,Ckm,Ckmm,M-CK,MCK,creatine kinase M chain,creatine kinase M-type, [mouse]

    CKM / CK-MM Related Studies

  • Goldblatt H. 1969, Laboratory Investigation. 21 (2): 126-8.
  • Hekimsoy Zeliha. et al., 2005, Endocrine Research. 31 (3): 171-5.
  • Döring F. et al., 2011, Scand J Med Sci Sports. 21(6):841-5.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"