0 products, total $0.+86-400-890-9989      Login |  Register 中文한국어

Browse By Molecule:

Your Position: Home > CIB2 Protein & Antibody

CIB2 Protein & Antibody

Calcium and integrin binding family member 2

CIB2 Products

CIB2 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CIB2 Human CIB2 Protein, Recombinant 12596-H07E

CIB2 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human CIB2 WB, ELISA CIB2 Antibody 12596-RP01
Human CIB2 WB, ELISA CIB2 Antibody (Antigen Affinity Purified) 12596-RP02
Human CIB2 ELISA CIB2 Antibody 12596-R001

CIB2 Related Areas

Signal Transduction>>Calcium Signaling>>Calcium Binding Protein>>CIB2

CIB2 Alternative Names

CIB2, KIP2, KIP 2 [Homo sapiens]

Cib2, , KIP 2, RP23-259G10.1, 2810434I23Rik, AI449053 [Mus musculus]

CIB2 Background

The Calmyrin2 (CaMy2, Cib2) is a novel calcium-binding protein with EF-hand found recently in skeletal muscle. Calcium signals are transmitted by Ca2+ binding proteins, which own the same myristoylated N-terminus. CaMy2 is myristoylated in vivo, similarly as CaMy1 and VILIP1, which in response to Ca-signal exhibit redistribution from the cytoplasm to membranes by so called Ca/myristoyl switch. CaMy2 was detected mainly in subcellular membranes and no Ca-dependent translocation was observed. In summary, although CaMy2 and CaMy1 undergo myristoylation in vivo, they do not exhibit Ca/myristoyl switch, but instead seem constitutively associated with subcellular membranes. In addition, observed differences in subcellular localisation of the two members of CaMy protein family suggest they are specialized to transmit Ca transients at their specific membrane locations mediating different Ca-signaling pathways.

CIB2 Related Studies

  1. Blazejczyk M, et al. (2006) Myristoylation and membranous localization of Calmyrin2, a new member of Neuronal Calcium-Sensor proteins. FENS Forum Abstracts. 3.
  2. Hollenbach AD, et al. (2006) The EF-hand calcium-binding protein calmyrin inhibits the transcriptional and DNA-binding activity of Pax3. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1574(3): 321-8.
  3. Blazejczyk M, et al. (2009) Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling. Archives of Biochemistry and Biophysics. 487(1): 66-78.



CIB2 related areas, pathways, and other information