Anti-CHL1 Antibody

Cat: 10143-RP01
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Anti-CHL1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CHL1 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human CHL1
Immunogen
Recombinant Human CHL1 protein (Catalog#10143-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human CHL1 (rh CHL1; Catalog#10143-H08H; NP_006605.2; Met 1-Gln 1080). Total IgG was purified by Protein A affinity chromatography .
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CHL1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CHL1 Antibody Alternative Names
Anti-CALL Antibody;Anti-L1CAM2 Antibody;Anti-LICAM2 Antibody
CHL1 Background Information

Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin typeⅢ domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease.

Full Name
cell adhesion molecule L1-like
References
  • Alevizopoulos A, et al. (1997) Regulation of the Transforming Growth Factor beta-responsive Transcription Factor CTF-1 by Calcineurin and Calcium/ Calmodulin-dependent Protein Kinase IV. The Journal of Biological Chemistry. 272: 23597-605.
  • Gerring SL, et al. (1990) The CHL1 (CTF 1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2 / M. EMBO J. 9 (13): 4347-58.
  • Wei MH, et al. (1998) In silico-initiated cloning and molecular characterization of a novel human member of the L1 gene family of neural cell adhesion molecules. Human Genetics. 103 (3): 355-64.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CHL1 Antibody Rabbit Polyclonal ELISA 51176-RP01
    Anti-CHL1 Antibody Rabbit Polyclonal ELISA 51176-T16
    Anti-CHL1 Antibody Mouse Monoclonal ELISA(Cap) 10143-MM05
    Anti-CHL1 Antibody Rabbit Polyclonal ELISA 10143-RP02
    Anti-CHL1 Antibody Mouse Monoclonal ELISA,ELISA(Det) 10143-MM01
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