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Properdin  Protein, Antibody, ELISA Kit, cDNA Clone

Properdin Related Area

Properdin Related Pathways

    Properdin Related Protein, Antibody, cDNA Gene, and ELISA Kits

    Properdin Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    Properdin Summary & Protein Information

    Properdin Background

    Subunit structure: In plasma, properdin exists as dimers, trimers or tetramers in the relative proportions of 26:54:20. {ECO:0000269|PubMed:15491616, ECO:0000269|PubMed:20382442}.
    Domain: TSP type-1 domains 0 and 6 bind to each other and mediate multimerization.
    Subcellular location: Secreted.
    Involvement in disease: DISEASE: Properdin deficiency (PFD) [MIM:312060]: Results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). {ECO:0000269|PubMed:10909851, ECO:0000269|PubMed:8871668, ECO:0000269|PubMed:9710744}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Sequence similarity: Contains 7 TSP type-1 domains. {ECO:0000255|PROSITE-ProRule:PRU00210}.
    General information above from UniProt

    Properdin Alternative Name

    PFC,PROPERDIN,BFD,PFD, [homo-sapiens]
    Pfc,BCFG, [mus-musculus]

    Properdin Related Studies

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