All Cofilin 2 reagents are produced in house and quality controlled, including 2 Cofilin 2 Antibody, 45 Cofilin 2 Gene, 1 Cofilin 2 IPKit, 1 Cofilin 2 Protein, 3 Cofilin 2 qPCR. All Cofilin 2 reagents are ready to use.
Recombinant Cofilin 2 proteins are expressed by E. coli with fusion tags as N-His.
Cofilin 2antibodies are validated with different applications, which are WB, IHC-P, ICC/IF, IF, IP.
Cofilin 2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Cofilin 2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.