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CFHR1

CFHR1 Protein & Antibody

Entrez Gene Summary for CFHR1


This CFHR1 gene encodes a secreted protein belonging to the complement factor H protein family. CFHR1 binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this CFHR1 gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]

OMIM-Description for CFHR1


Timmann et al. (1991) isolated 2 differently glycosylated forms of a human serum protein antigenically related to complement factor H (CFH; 134370). Skerka et al. (1991) isolated a cDNA clone for this protein that predicted a protein sequence of 327 amino acids with a leader sequence. The secreted part of the protein comprised 5 tandem repeating units, termed short consensus repeats (SCRs). The 3-prime end showed sequence homology to the 3-prime end of human complement factor H. Skerka et al. (1991) also isolated a cDNA clone that appeared to represent a transcribed pseudogene, since it contained a stop codon (TAA) within SCR 1. See also Zipfel and Skerka (1994).

.zh=CFHR1


Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene.

CFHR1 Alternative Names

CFHL,CFHL1,CFHL1P,CFHR1P,complement factor H-related 1 pseudogene,complement factor H-related protein 1,FHR1,FHR-1,H factor (complement)-like 1,H factor (complement)-like 2,h factor-like protein 1,H36,H36-1,H36-2,H-factor-like 1,HFL1,HFL2, [human]
AI194696,Cfhl1,CFHRB,complement component factor h-like 1,complement factor H-related protein, [mouse]

CFHR1 Related Products

CFHR1 Proteins

Product nameProduct name
Human CFHR1 Protein (His Tag)

CFHR1 Antibodies

Product nameProduct name
CFHR1 Antibody, Rabbit PAb, Antigen Affinity Purified

CFHR1 cDNA Clones

Product nameProduct name
Mouse CFHR1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, C-Flag tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, C-His tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, C-Myc tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, C-HA tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, N-Flag tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, N-His tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, N-Myc tagMouse CFHR1 Gene ORF cDNA clone expression plasmid, N-HA tagMouse CFHR1 Gene ORF cDNA clone expression plasmid

CFHR1 ELISA

Product nameProduct name
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"