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Human CFHR1 Protein (His Tag)
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Human CFHR1 Protein (His Tag) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
12822-H08H  
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Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Complement factor H-related 1 Protein Datasheet

 

CFHR1 Protein Price Inquiry ( Available Sizes )

CFHR1 Protein Product Information

Synonym : CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2
Protein Construction:

A DNA sequence encoding the human CFHR1 (Q03591) (Met1-Arg330) was expressed with a polyhistidine tag at the C-terminus.

Source: Human
Expression Host: Human Cells

CFHR1 Protein QC Testing

Purity: > 95% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

CFHR1 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 19
Molecular Mass:

The recombinant human CFHR1 consists of  323 amino acids and predicts a molecular mass of 37.2 KDa. It migrates as an approximately 45 KDa band in SDS-PAGE under reducing conditions.

Formulation: Lyophilized from sterile PBS, pH 7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

CFHR1 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CFHR1 Protein Related Products & Topics

Related Areas:

Proteins:

Antibodies:

CFHR1 Protein Description

CFHR1 is a member of the complement factor H protein family. It is a secreted protein which binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). CFHR1 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.

References

  1. Martínez-Barrica. et al., 2012, Invest Ophthalmol Vis Sci. 53 (3): 1087-94.
  2. Leban N. et al., 2012, Int J Immunogenet. 39 (2): 110-3.
  3. Kubista KE. et al., 2011, Mol Vis. 17: 2080-92.
 

 

CFHR1 related areas, pathways, and other information

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"