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|Catalog||Size (Price)||Quantity||In Stock||Operation|
Complement factor H-related 1 Protein Datasheet
CFHR1 Protein Price Inquiry ( Available Sizes )
CFHR1 Protein Product Information
|Synonym :||CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2|
A DNA sequence encoding the human CFHR1 (Q03591) (Met1-Arg330) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
CFHR1 Protein QC Testing
|Purity:||> 95% as determined by SDS-PAGE||SDS-PAGE:
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Glu 19|
The recombinant human CFHR1 consists of 323 amino acids and predicts a molecular mass of 37.2 KDa. It migrates as an approximately 45 KDa band in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH 7.4.
CFHR1 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
CFHR1 Protein Related Products & Topics
CFHR1 Protein Description
CFHR1 is a member of the complement factor H protein family. It is a secreted protein which binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). CFHR1 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.
- Martínez-Barrica. et al., 2012, Invest Ophthalmol Vis Sci. 53 (3): 1087-94.
- Leban N. et al., 2012, Int J Immunogenet. 39 (2): 110-3.
- Kubista KE. et al., 2011, Mol Vis. 17: 2080-92.