Anti-CES2 Antibody

Cat: 50515-RP01
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All CES2 Reagents
Anti-CES2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CES2 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse CES2
Recombinant Mouse CES2 / Carboxylesterase 2 protein (Catalog#50515-M08H)
Produced in rabbits immunized with purified, recombinant Mouse CES2 / Carboxylesterase 2 (rM CES2 / Carboxylesterase 2; Catalog#50515-M08H; NP_663578.1; Met 1-Lys 557). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CES2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CES2 Antibody Alternative Names
Anti-ces2A3 Antibody
CES2 Background Information

Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

Full Name
carboxylesterase 2
  • Imai T. et al. (2006) Human carboxylesterase isozymes: catalytic properties and rational drug design. Drug metab pharmacokinet. 21 (3): 173-85.
  • Guang Xu, et al. (2002) Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan. Clin Cancer Res. 8: 2605.
  • Zhang, et al. (2002) Comprehensive Evaluation of Carboxylesterase-2 Expression in Normal Human Tissues Using Tissue Array Analysis. Applied Immunohistochemistry & Molecular Morphology. 10 (4): 374-80.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CES2 Antibody Rabbit Polyclonal ELISA,IHC-P 50515-RP02
    Anti-CES2 Antibody Rabbit Polyclonal ELISA 10380-RP01
    Anti-CES2 Antibody Rabbit Polyclonal ELISA 10380-RP02
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