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CEACAM8 / CD66b Antibody, Rabbit MAb
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CEACAM8 / CD66b Antibody, Rabbit MAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
11729-R013  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

CEACAM8 / CD66b Antibody Datasheet

  Order or Inquire for CEACAM8 / CD66b Antibody product Quality antibodies Antibody production services
  Detection limit is 0. 00245 ng/well in ELISA
 

CEACAM8 / CD66b Antibody Product Information

Immunogen :

Recombinant Human CEACAM8 / CD66b protein (Catalog#11729-H08H)

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID :

013

Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM8 / CD66b (rh CEACAM8 / CD66b; Catalog#11729-H08H; NP_001807.2; Met 1-Ser 319).

CEACAM8 / CD66b Antibody Usage Guide

Specificity :

Human CEACAM8 / CD66b

Direct ELISA : This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CEACAM8. The detection limit for Human CEACAM8 is approximately 0. 00245 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CEACAM8 / CD66b Antibody Related Products & Topics

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Proteins:

Antibodies:

CEACAM8 / CD66b Antibody Background

Carcinoembryonic antigen-related cell adhesion molecule 8, also known as carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, CEACAM8, CD66b and CGM6, is a cell membrane protein which belongs to theimmunoglobulin superfamily and CEA family. CEACAM8 / CD66b contains twoIg-like C2-type (immunoglobulin-like) domains and oneIg-like V-type (immunoglobulin-like) domain. CEACAM8 / CD66b is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. It is an activation marker for human granulocytes. CEACAM8 / CD66b is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. There are two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, and seven CEACAM has been identified in humans including type I transmembrane proteins (CEACAM-1, CEACAM-3, CEACAM-4) and GPI-linked molecules (CEACAM-5, CEACAM-6, CEACAM-7, CEACAM-8). CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.

References

  1. Oikawa,S. et al., 2000, Biochem Biophys Res Commun278 (3):564-8.
  2. Lasa,A. et al., 2008, Ann Hematol. 87 (3): 205-11.
  3. Skubitz, KM. et al., 2001,J Pept Res. 58 (6): 515-26.
  4. Yoon, J.et al., 2007,J Immunol. 179 (12): 8454-62.
  5. Ramachandran P. et al., 2006, J. Proteome Res. 5:1493-503.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"