CEACAM6 Protein & Antibody (CD66c)

Carcinoembryonic antigen (CEA)-related Cell Adhesion Molecule 6 (Cluster of Differentiation 66c)

CEACAM6 Protein & Antibody Products

CEACAM6 Protein, Recombinant

Molecule	Species	Description	Cat. No
CEACAM6/CD66c	Human	CEACAM6/CD66c Protein, Recombinant	10823-H08H

CEACAM6 Antibody

Molecule	Application	Description	Cat. No
Human CEACAM6/CD66c	WB, ELISA	Mouse Monoclonal Antibody	10823-MM05
Human CEACAM6/CD66c	WB, ELISA	Mouse Monoclonal Antibody	10823-MM06
Human CEACAM6/CD66c	WB, ELISA	Rabbit Monocolonal Antibody	10823-RM03
Human CEACAM6/CD66c	FCM	CEACAM6 / CD66c Antibody ( FITC )	10823-RM03-F
Human CEACAM6/CD66c	WB, FCM	CEACAM6 / CD66c Antibody ( FITC )	10823-R408-F
Human CEACAM6/CD66c	ELISA	CEACAM6/CD66c Antibody, Rabbit MAb	10823-R408
Human CEACAM6/CD66c	ELISA	Rabbit Polycolonal Antibody	10823-RP01
Human CEACAM6/CD66c	WB ELISA	CD66c / CEACAM6 Antibody (Biotin conjugated, Antigen Affinity Purified)	10823-RP03B
Human CEACAM6/CD66c	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10823-RP04

CEACAM6 ELISA Kit

Molecule	Application	Description	Cat. No
Human CEACAM6/CD66c	ELISA	CEACAM6/CD66c ELISA Kit	SEK10823

CEACAM6 cDNA Clone

Molecule	Species	Description	Cat. No
CEACAM6/CD66c	Human	Homo sapiens CEACAM6/CD66c cDNA Clone(NM_002483.4)	HG10823-M

CEACAM6 Related Areas

Cancer>>Cancer Biomarkers>>CEACAM6/CD66c

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>CEACAM6/CD66c

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers>>CEACAM6/CD66c

CEACAM6 Alternative Names

CEACAM6, CD66c, CEAL, NCA [Homo sapiens]

CEACAM6 Background

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.

CEACAM6 Related Studies

1. Duxbury MS, et al. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 23(34): 5834-42.
2. Lewis-Wambi JS, et al. (2008) Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells. Eur J Cancer. 44(12): 1770-9.