Anti-CEACAM6 Antibody (FITC)

Cat: 10823-R408-F
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Anti-CEACAM6 Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Product name
Anti-CEACAM6 Antibody (FITC)
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human CEACAM6
Immunogen
Human cell-derived rhCEACAM6 (Catalog#10823-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM6 / CD66c (rh CEACAM6 / CD66c; 10823-H08H; Met 1-Gly 320; NP_002474.3) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Source
Monoclonal Rabbit IgG Clone #408
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
FITC
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-CEACAM6 Antibody (FITC) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CEACAM6 Antibody (FITC) (Rabbit Monoclonal antibody) Images
Human CEACAM6/CD66c Flow Cytometry (FC) 2607
Profile of anti-CEACAM6 (CD66c) reactivity on SK-BR3 cells analyzed by flow cytometry.
Anti-CEACAM6 Antibody (FITC) Alternative Names
Anti-CD66c Antibody;Anti-CEA Antibody;Anti-CEAL Antibody;Anti-NCA Antibody
CEACAM6 Background Information

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.

Full Name
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
References
  • Duxbury MS, et al. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 23(34): 5834-42.
  • Lewis-Wambi JS, et al. (2008) Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells. Eur J Cancer. 44(12): 1770-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CEACAM6 Antibody Rabbit Monoclonal ELISA 10823-RM02
    Anti-CEACAM6 Antibody Rabbit Monoclonal ELISA 10823-RM01
    Anti-CEACAM6 Antibody (PerCP) Rabbit Monoclonal FCM 10823-R408-C
    Anti-CEACAM6 Antibody Rabbit Monoclonal WB,ELISA,FCM,ICC/IF,IF 10823-R408
    Anti-CEACAM6 Antibody (PE) Mouse Monoclonal FCM 10823-MM12-P
    Anti-CEACAM6 Antibody Mouse Monoclonal ELISA 10823-MM06
    Anti-CEACAM6 Antibody Mouse Monoclonal ELISA,FCM 10823-MM05
    Anti-CEACAM6 Antibody Mouse Monoclonal FCM 10823-MM12
    Anti-CEACAM6 Antibody (FITC) Rabbit Monoclonal FCM 10823-RM03-F
    Anti-CEACAM6 Antibody (APC) Mouse Monoclonal FCM 10823-MM12-A
    Anti-CEACAM6 Antibody Rabbit Polyclonal ELISA 10823-RP01
    Anti-CEACAM6 Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 10823-RM03
    Anti-CEACAM6 Antibody (APC) Rabbit Monoclonal FCM 10823-R408-A
    Anti-CEACAM6 Antibody (PE) Mouse Monoclonal FCM 10823-MM05-P
    Anti-CEACAM6 Antibody Rabbit Polyclonal ELISA,IHC-P 10823-T24
    Anti-CEACAM6 Antibody Rabbit Polyclonal ELISA 10823-RP04
    Anti-CEACAM6 Antibody (PE) Rabbit Monoclonal FCM 10823-R408-P
    Anti-CEACAM6 Antibody Rabbit Monoclonal ELISA(Det) 10823-R341
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