**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-CEACAM6 rabbit monoclonal antibody at 1:500 dilution
Lane A: Jurkat Whole Cell LysateLysates/proteins at 30 μg per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.
Performed under reducing conditions.Predicted band size:37 kDa
Observed band size:52 kDa
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-CEACAM6 Antibody (APC)||Mouse||Monoclonal||FCM||10823-MM12-A|
|Anti-CEACAM6 Antibody (PE)||Mouse||Monoclonal||FCM||10823-MM12-P|
|Anti-CEACAM6 Antibody (PerCP)||Rabbit||Monoclonal||FCM||10823-R408-C|
|Anti-CEACAM6 Antibody (APC)||Rabbit||Monoclonal||FCM||10823-R408-A|
|Anti-CEACAM6 Antibody (PE)||Mouse||Monoclonal||FCM||10823-MM05-P|
|Anti-CEACAM6 Antibody (FITC)||Rabbit||Monoclonal||FCM||10823-R408-F|
|Anti-CEACAM6 Antibody (PE)||Rabbit||Monoclonal||FCM||10823-R408-P|
|Anti-CEACAM6 Antibody (FITC)||Rabbit||Monoclonal||FCM||10823-RM03-F|