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Human CEACAM5 / CD66e ELISA Pair Set
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Human CEACAM5 / CD66e ELISA Pair Set PDF Download

Catalog   Size (Price) Quantity In Stock Operation
SEK11077  

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Human CEACAM5 / CD66e ELISA Pair Set

Order or Inquire for CEACAM5 / CD66e ELISA Pair Set
High affinity Human CEACAM5 / CD66e ELISA Pair Set
Detection limit - 31.25 pg/ml
Affordable price and 30%-80% cost saving for Bulk order
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Human CEACAM5 / CD66e ELISA Pair Set Related Products & Topics

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Background

CEACAM5, also known as CEA or D66e, belongs to the large CEACAM subfamily of immunoglobulin superfamily. CEACAM5 is expressed primarily by epithelial cells, and is synthesized as a glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. CEACAM5 contains one Ig-like V-type domain at the N-terminus, followed by six Ig-like C2-type domain and a GPI anchor, and exists as a homodimer. It functions as a homotypic intercellular adhesion molecule and serves as a widely used tumor marker, since it is expressed at higher levels in tumorous tissues than in corresponding normal tissues. CEACAM5 has also been shown to contribute to tumorigenicity by inhibiting cellular differentiation. In addition, CEACAM5 is identified as the host receptor for the Dr family of adhesins of E.Coli, and the binding of E.coli Dr adhesins leads to dissociation of the CEACAM5 homodimer.

 

 

CEACAM5/CD66e related areas, pathways, and other information

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"