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>Human Cell Expressed
>Rat CEACAM1 / CD66a Protein (His Tag)
|Catalog||Size (Price)||Quantity||In Stock||Operation|
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) Protein Datasheet
CEACAM1 / CD66a Protein Price Inquiry ( Available Sizes )
CEACAM1 / CD66a Protein Product Information
A DNA sequence encoding the rat CEACAM1(Met1-Ser422) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
CEACAM1 / CD66a Protein QC Testing
|Purity:||> 95 % as determined by SDS-PAGE||SDS-PAGE:
CEACAM1 / CD66a protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Gln 35|
The recombinant rat CEACAM1 comprises 399 amino acids and predicts a molecular mass of 44.9 kDa. The apparent molecular mass of the recombinant protein is approximately 66-76 kDa in SDS-PAGE under reducing conditions due to glycosylation.
|Formulation:||Lyophilized from sterile PBS, pH 7.4.
CEACAM1 / CD66a Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
CEACAM1 / CD66a Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|CEACAM1/CD66a||Human||CEACAM1/CD66a Protein, Recombinant||10822-H08H|
|CEACAM1/CD66a||Mouse||CEACAM1/CD66a Protein, Recombinant||50571-M08H|
|CEACAM1/CD66a||Rat||CEACAM1 / CD66a Protein, Recombinant||80224-R08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|WB, ELISA, IHC||Mouse Monocolonal Antibody||10822-MM02|
|ELISA||Rabbit Polycolonal Antibody||10822-RP01|
|WB, ELISA||Rabbit Polyclonal Antibody (Antigen Affinity Purified)||10822-RP04|
|WB, ELISA||Rabbit Monoclonal Antibody||10822-R006|
|WB, ELISA||CEACAM1 / CD66a Antibody||50571-RP01|
|WB, ELISA||CEACAM1 / CD66a Antibody (Antigen Affinity Purified)||50571-RP02|
CEACAM1 / CD66a Protein Description
Carcinoembryonic antigen (CEA)-related cell adhesion molecule 1 (CEACAM1), also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. There are two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, and seven CEACAM has been identified in humans including type I transmembrane proteins (CEACAM-1, CEACAM-3, CEACAM-4) and GPI-linked molecules (CEACAM-5, CEACAM-8). The highly glycosylated CEACAM1 contains one N-terminal V-type I g-like domain and three C2-type I g-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
- Hinoda Y. et al., 1988, Proc Natl Acad Sci. 85: 6959-63.
- Zalzali H. et al., 2008, Oncogene. 27: 7131-8.
- Erqun S. et al., 2000, Mol Cell. 5: 311-20.
- Oliveira-Ferrer L. et al., 2004, Cancer Res. 64: 8932-8.