CEACAM1 Protein & Antibody (CD66a)

Carcinoembryonic antigen (CEA)-related Cell Adhesion Molecule 1 (Cluster of Differentiation 66a)

CEACAM1 Protein & Antibody Products

CEACAM1 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CEACAM1/CD66a	Human	CEACAM1/CD66a Protein, Recombinant	10822-H08H
CEACAM1/CD66a	Mouse	CEACAM1/CD66a Protein, Recombinant	50571-M08H
CEACAM1/CD66a	Rat	CEACAM1 / CD66a Protein, Recombinant	80224-R08H

CEACAM1 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CEACAM1/CD66a	WB, ELISA, IHC	Mouse Monocolonal Antibody	10822-MM02
Human CEACAM1/CD66a	ELISA	Rabbit Polycolonal Antibody	10822-RP01
Human CEACAM1/CD66a	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10822-RP04
Human CEACAM1/CD66a	WB, ELISA	Rabbit Monoclonal Antibody	10822-R006
Mouse CEACAM1/CD66a	WB, ELISA	CEACAM1 / CD66a Antibody	50571-RP01
Mouse CEACAM1/CD66a	WB, ELISA	CEACAM1 / CD66a Antibody (Antigen Affinity Purified)	50571-RP02

CEACAM1 ELISA Kit

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CEACAM1/CD66a	ELISA	CEACAM1/CD66a ELISA Kit	SEK10822

CEACAM1 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CEACAM1/CD66a	Human	CEACAM1 transcript variant 1 cDNA Clone / ORF Clone	HG10822-M
CEACAM1/CD66a	Mouse	Mus musculus CEACAM1/CD66a cDNA Clone	MG50571-M

CEACAM1 Related Areas

Cardiovascular>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CEACAM1/CD66a

Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CEACAM1/CD66a

Cancer>>Cancer Biomarkers>>CEACAM1/CD66a

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>CEACAM1/CD66a

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers>>CEACAM1/CD66a

CEACAM1 Alternative Names

CEACAM1, CD66a, BGP, BGP1, BGPI [Homo sapiens]

Ceacam1, CD66a, Bgp, Bgp1, C-CAM, Cc1, Cea-1, Cea-7, Cea1, Cea7, Hv-2, Hv2, MHVR, MHVR1, Mhv-1, bb-1, mCEA1, mmCGM1, mmCGM1a, mmCGM2 [Mus musculus]

CEACAM1 Background

The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

CEACAM1 Related Studies

1. Gray-Owen SD, et al. (2006) CEACAM1: contact-dependent control of immunity. Nat Rev Immunol. 6(6): 433-46.
2. Gu A, et al. (2009) Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture. Exp Cell Res. 315(10): 1668-82.
3. Wong C, et al. (2009) CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo. Blood. 113(8): 1818-28.