**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-CEACAM1 rabbit polyclonal antibody at 1:500 dilution
Lane A: HepG2 Whole Cell LysateLysates/proteins at 30 μg per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.
Performed under reducing conditions.Predicted band size:58 kDa
Observed band size:100 kDa
(We are unsure as to the identity of these extra bands.)
The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: IHC Antibodies Immune Checkpoint Detection: ICC Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-CEACAM1 Antibody (APC)||Mouse||Monoclonal||FCM||80224-MM03-A|
|Anti-CEACAM1 Antibody (PE)||Mouse||Monoclonal||FCM||80224-MM03-P|
|Anti-CEACAM1 Antibody (PerCP)||Rabbit||Monoclonal||FCM||50571-R117-C|
|Anti-CEACAM1 Antibody (FITC)||Rabbit||Monoclonal||FCM||50571-R117-F|
|Anti-CEACAM1 Antibody (APC)||Rabbit||Monoclonal||FCM||50571-R117-A|
|Anti-CEACAM1 Antibody (PE)||Rabbit||Monoclonal||FCM||50571-R117-P|
|Anti-CEACAM1 Antibody (APC)||Mouse||Monoclonal||FCM||10822-MM02-A|
|Anti-CEACAM1 Antibody (APC)||Rabbit||Monoclonal||FCM||10822-R103-A|
|Anti-CEACAM1 Antibody (PE)||Mouse||Monoclonal||FCM||10822-MM02-P|
|Anti-CEACAM1 Antibody (FITC)||Mouse||Monoclonal||FCM||10822-MM02-F|
|Anti-CEACAM1 Antibody (PE)||Rabbit||Monoclonal||FCM||10822-R103-P|