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CEACAM1 / CD66a Antibody (PE), Rabbit MAb

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Human CEACAM1 Antibody Product Information
Immunogen:Recombinant Human CEACAM1 / CD66a protein (Catalog#10822-H08H)
Clone ID:103
Ig Type:Rabbit IgG
Concentration:5 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM1 / CD66a (rh CEACAM1 / CD66a; Catalog#10822-H08H; NP_001020083.1; Met1-Gly428) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Human CEACAM1 Antibody Usage Guide
Specificity:Human CEACAM1 / CD66a
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Human CEACAM1 Antibody FC Application Image
CEACAM1 / CD66a Antibody (PE), Rabbit MAb, Flow cytometric
[Click to enlarge image]
Flow cytometric analysis of anti-Human CEACAM1 on HT29 cells.
Other CEACAM1 Antibody Products
CEACAM‑1/CD66a Background

The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

Human CEACAM‑1/CD66a References
  • Gray-Owen SD, et al. (2006) CEACAM1: contact-dependent control of immunity. Nat Rev Immunol. 6(6): 433-46.
  • Gu A, et al. (2009) Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture. Exp Cell Res. 315(10): 1668-82.
  • Wong C, et al. (2009) CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo. Blood. 113(8): 1818-28.
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    Catalog: 10822-R103-P-50
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    50 Tests
    100 Tests
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