CDKL2 Protein

Cyclin-Dependent Kinase-Like 2 (CDC2-related kinase)

CDKL2 Products

CDKL2 Protein, Recombinant

Molecule	Species	Description	Cat. No
CDKL2	Human	CDKL2 Protein, Recombinant	11191-H07B

CDKL2 cDNA Clone

Molecule	Species	Description	Cat. No
CDKL2	Human	Human CDKL2 cDNA Clone / ORF Clone	HG11191-M

CDKL2 Related Areas

Enzyme>>Protein Kinase>>Intracellular Kinase>>Cyclin-Dependent Kinase (CDK)>>CDKL2

Signal Transduction>>Protein Kinase>>Intracellular Kinase>>CDKL2

CDKL2 Alternative Names

CDKL2, KKIAMRE, P56 [Homo sapiens]

Cdkl2, 5330436L21Rik, AI505225, KKIAMRE, Kkm, MGC144031, MGC144032 [Mus musculus]

CDKL2 Background

Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus, amygdala, and dorsal thalamus. The high expression in these brain regions suggests that Cdkl2 may have functions in congnition and emotion processes. Cdkl2 accumulates primarily in the cytoplasm, with lower levels in the nucleus.

CDKL2 Related Studies

1. Sassa T, et al. (2003) Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus. Cell and Tissue Research. 315 (2): 147-56.
2. Rosenblatt J, et al. (1992) Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. PNAS. 89 (7): 2824-8.
3. Mironov V, et al.  (1999) Cyclin-Dependent Kinases and Cell Division in Plants-The Nexus. The Plant Cell. 11 (4): 509-22.