All CD93 reagents are produced in house and quality controlled, including 16 CD93 Antibody, 3 CD93 ELISA, 26 CD93 Gene, 3 CD93 Lysate, 3 CD93 Protein, 2 CD93 qPCR. All CD93 reagents are ready to use.
Recombinant CD93 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc.
CD93antibodies are validated with different applications, which are ELISA, FCM, ELISA(Cap), IHC-P, ELISA(Det).
CD93cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD93 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD93ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.