CD90 / THY-1 Protein & Antibody

Cluster of Differentiation 90 / Thymus cell antigen 1

CD90 / THY-1 Products

CD90 / THY-1 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
CD90/THY-1	Mouse	CD90/THY1 Protein, Recombinant	50461-M08H

CD90 / THY-1 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No
Mouse CD90/THY-1	WB, ELISA	CD90/THY-1 Antibody, Rabbit PAb	50461-RP01
Mouse CD90/THY-1	WB, ELISA	CD90/THY-1 Antibody, Rabbit PAb (Antigen Affinity Purified)	50461-RP02

CD90 / THY-1 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
CD90/THY-1	Mouse	Mus musculus CD90/THY1 cDNA Clone	MG50461-M

CD90 / THY-1 Related Areas

Biomarkers>>Neuronal Cell Markers>>CD90/THY-1

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD90/THY-1

Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD90/THY-1

CD90 / THY-1 Alternative Names

CD90, THY-1, CDw90, FLJ33325 [Homo sapiens]

CD90, Thy-1, Thy1, T25, Thy-1.2, Thy1.1, Thy1.2 [Mus musculus]

CD90 / THY-1 Background

Mouse Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.

CD90 / THY-1 Related Studies

1. Rege TA, et al. (2006) Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB J. 20(8): 1045-54.
2. Fiegel HC, et al. (2008) Lack of Thy1 (CD90) expression in neuroblastomas is correlated with impaired survival. Pediatr Surg Int. 24(1): 101-5.
3. Bradley JE, et al. (2009) Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype. Biofactors. 35(3): 258-65.
4. Kisselbach L, et al. (2009) CD90 Expression on human primary cells and elimination of contaminating fibroblasts from cell cultures. Cytotechnology. 59(1): 31-44.