All CD9 reagents are produced in house and quality controlled, including 5 CD9 Antibody, 39 CD9 Gene, 1 CD9 Lysate, 1 CD9 Protein, 3 CD9 qPCR. All CD9 reagents are ready to use.
Recombinant CD9 proteins are expressed by HEK293 Cells with fusion tags as C-His.
CD9antibodies are validated with different applications, which are FCM, ICC/IF, IF.
CD9cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD9 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD9 is a member of the transmembrane 4 superfamily, which is also known as the tetraspanin family. CD9 is a cell surface glycoprotein with 4 hydrophobic domains that is described to complex with integrins and other transmembrane 4 superfamily members. It is found expressed on the surface of the exosomes. The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activation, growth and motility. Besides, CD9 seems to be a key role in the egg-sperm fusion during the mammalian fertilization processes. CD9 is found on the membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli.