CD9 Protein & Antibody

Cluster of Differentiation 9

CD9 Products

CD9 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD9	Human	CD9 Protein, Recombinant	11029-H08H

  11029-H08H:

1.Immobilized human CD19 at 2 µg/ml (100 µl/well) can bind biotinylated human CD9 with a linear ranger of 0.032-0.8 µg/ml. Measured by its binding ability in a functional ELISA.

2. Immobilized mouse CD19 at 20 µg/ml (100 µl/well) can bind biotinylated human CD9 with a linear ranger of 0.032-0.8 µg/ml. Measured by its binding ability in a functional ELISA.

3.Immobilized human CD21 at 2 µg/ml (100 µl/well) can bind biotinylated human CD9. The EC50 of biotinylated human CD9 is 1.76 µg/ml. Measured by its binding ability in a functional ELISA.

CD9 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD9	FCM	CD9 Antibody	11029-MM01-F
Human CD9	FCM	CD9 Antibody ( PE )	11029-MM01-P

CD9 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD9	Human	Homo sapiens CD9 cDNA Clone	HG11029-M
CD9	Mouse	Mouse CD9 cDNA gene Clone / ORF gene Clone	MG50395-M

CD9 Related Areas

Cardiovascular>>Platelet>>CD9

Immunology>>Cluster of Differentiation>>CD9

Stem Cell>>Embryonic Stem Cell (ESC)>>Embryonic Stem Cell Marker>>CD9

Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CD9

CD9 Alternative Names

CD9, GIG2, 5H9, BA2, BTCC-1, DRAP-27, MIC3, MRP-1, P24, TSPAN29 [Homo sapiens]

Cd9, Tspan29 [Mus musculus]

 

CD9 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD9 is a member of the transmembrane 4 superfamily, which is also known as the tetraspanin family. CD9 is a cell surface glycoprotein with 4 hydrophobic domains that is described to complex with integrins and other transmembrane 4 superfamily members. It is found expressed on the surface of the exosomes. The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activation, growth and motility. Besides, CD9 seems to be a key role in the egg-sperm fusion during the mammalian fertilization processes. CD9 is found on the membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli.

CD9 Related Studies

1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125–35.
3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
4. François Le Naour, et al. (2000) Severely Reduced Female Fertility in CD9-Deficient Mice. Science. 287(5451): 319-21.