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CD8a Antibody, Rabbit PAb, Antigen Affinity Purified

  • CD8a Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
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Ferret CD8A Antibody Product Information
Immunogen:Recombinant Ferret CD8a protein (Catalog#60001-F08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Ferret CD8a (rF CD8a; Catalog#60001-F08H; ABS50091.1; Met 1-Glu 186). CD8a specific IgG was purified by Ferret CD8a affinity chromatography.
Ferret CD8A Antibody IHC Application Image
CD8a Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of ferret CD8A in ferret spleen with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other CD8A Antibody Products
Reactivity: Human  
Application: ELISA  WB  
  • Slide 1
10980-T48-50
10980-T48-200
10980-T48-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: 
    10980-MM07-50
    10980-MM07-200
    10980-MM07-100
    10980-MM07-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    10980-MM28-50
    10980-MM28-200
    10980-MM28-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10980-MM22-50
      10980-MM22-200
      10980-MM22-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: 
      • Slide 1
      10980-MM28-A-25
      10980-MM28-A-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10980-RP01-400
        10980-RP01-200
        10980-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10980-MM20-F-25
        10980-MM20-F-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10980-MM25-50
          10980-MM25-200
          10980-MM25-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: IHC-P  
          • Slide 1
          10980-R081-50
          10980-R081-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            10980-MM04-50
            10980-MM04-200
            10980-MM04-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Human  
            Application: 
              10980-MM01-50
              10980-MM01-200
              10980-MM01-100
              10980-MM01-1
              50 µg 
              200 µg 
              100 µg 
              1 mg 
              Add to Cart
              Reactivity: Human  
              Application: FCM  
              • Slide 1
              10980-MM28-F-25
              10980-MM28-F-100
              25 Test 
              100 Tests 
              Add to Cart
              Reactivity: Mouse  
              Application: FCM  
              • Slide 1
              • Slide 1
              50389-R208-A-25
              50389-R208-A-100
              25 Test 
              100 Tests 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  
                50389-R012-50
                50389-R012-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  50389-RP02-50
                  50389-RP02-200
                  50389-RP02-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: FCM  
                  • Slide 1
                  50389-R208-C-25
                  50389-R208-C-100
                  25 Test 
                  100 Tests 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: FCM  IF  ICC/IF  
                  • Slide 1
                  • Slide 1
                  50389-R208-50
                  50389-R208-100
                  50 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: FCM  
                  • Slide 1
                  • Slide 1
                  50389-R208-P-25
                  50389-R208-P-100
                  25 Test 
                  100 Tests 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: ELISA  
                    50389-RP01-200
                    50389-RP01-100
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Mouse  
                    Application: 
                      50389-R016-50
                      50389-R016-100
                      50389-R016-1
                      50 µg 
                      100 µg 
                      1 mg 
                      Add to Cart
                      Reactivity: Mouse  
                      Application: FCM  
                      • Slide 1
                      • Slide 1
                      50389-R208-F-25
                      50389-R208-F-100
                      25 Test 
                      100 Tests 
                      Add to Cart
                      Reactivity: Ferret  
                      Application: FCM  
                      • Slide 1
                      60001-R073-F-25
                      60001-R073-F-100
                      25 Test 
                      100 Tests 
                      Add to Cart
                      Reactivity: Ferret  
                      Application: ELISA  
                        60001-R080-50
                        60001-R080-100
                        50 µg 
                        100 µg 
                        Add to Cart
                        Reactivity: Ferret  
                        Application: 
                          60001-R070-50
                          60001-R070-100
                          60001-R070-1
                          50 µg 
                          100 µg 
                          1 mg 
                          Add to Cart
                          Reactivity: Ferret  
                          Application: FCM  
                          • Slide 1
                          60001-R082-A-25
                          60001-R082-A-100
                          25 Test 
                          100 Tests 
                          Add to Cart
                          Reactivity: Ferret  
                          Application: FCM  
                          • Slide 1
                          60001-R082-P-25
                          60001-R082-P-100
                          25 Test 
                          100 Tests 
                          Add to Cart
                          Reactivity: Ferret  
                          Application: FCM  
                          • Slide 1
                          60001-R073-C-25
                          60001-R073-C-100
                          25 Test 
                          100 Tests 
                          Add to Cart
                          Reactivity: Ferret  
                          Application: ELISA  
                            60001-RP01-400
                            60001-RP01-200
                            60001-RP01-100
                            400 µg 
                            200 µg 
                            100 µg 
                            Add to Cart
                            Reactivity: Ferret  
                            Application: FCM  
                            • Slide 1
                            60001-R082-F-25
                            60001-R082-F-100
                            25 Test 
                            100 Tests 
                            Add to Cart
                            Reactivity: Ferret  
                            Application: FCM  
                            • Slide 1
                            60001-R073-A-25
                            60001-R073-A-100
                            25 Test 
                            100 Tests 
                            Add to Cart
                            Reactivity: Ferret  
                            Application: ELISA  
                              60001-MM02-50
                              60001-MM02-200
                              60001-MM02-100
                              60001-MM02-1
                              50 µg 
                              200 µg 
                              100 µg 
                              1 mg 
                              Add to Cart
                              Reactivity: Ferret  
                              Application: FCM  
                              • Slide 1
                              60001-R073-P-25
                              60001-R073-P-100
                              25 Test 
                              100 Tests 
                              Add to Cart
                              Reactivity: Ferret  
                              Application: FCM  
                              • Slide 1
                              60001-R082-C-25
                              60001-R082-C-100
                              25 Test 
                              100 Tests 
                              Add to Cart

                              Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

                              Lane A: NIH3T3 Whole Cell Lysate

                              Lane B: Hela Whole Cell Lysate

                              Lysates/proteins at 30 μg per lane.

                              Secondary

                              Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

                              Developed using the ECL technique.

                              Performed under reducing conditions.

                              Predicted band size:15 kDa

                              Observed band size:17 kDa

                              CD8/CD8 alpha/Leu-2 Background

                              T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I  membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

                              Ferret CD8/CD8 alpha/Leu-2 References
                              References Devine, L. et al., 2000, J Immunol. 164 (2): 833-8. Arcaro, A. et al., 2000, J Immunol. 165 (4): 2068-76. Saha, K. et al., 2001, Nat Med. 7 (1): 65-72. Romero, P. et al., 2005, Eur J Immunol. 35 (11): 3092-4.
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                              Catalog: 60001-RP02-50
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                              Datasheet & Documentation

                              All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                              Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"