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CD8a Antibody, Rabbit PAb, Antigen Affinity Purified
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CD8a Antibody, Rabbit PAb, Antigen Affinity Purified PDF Download

Catalog   Size (Price) Quantity In Stock Operation
60001-RP02  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

CD8a Antibody ( Antigen Affinity Purified ) Datasheet

  Order or Inquire for CD8a Antibody product Quality antibodies Antibody production services
  Detection limit is 0.00975 ng/well in ELISA
 

CD8a Antibody Product Information

Immunogen :

Recombinant Ferret CD8a protein (Catalog#60001-F08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

Produced in rabbits immunized with purified, recombinant Ferret CD8a (rF CD8a; Catalog#60001-F08H; ABS50091.1; Met 1-Glu 186). CD8a specific IgG was purified by Ferret CD8a affinity chromatography.

CD8a Antibody Usage Guide

Specificity :

Ferret CD8a

Immunochemistry :

IHC-P: 0.1-2 μg/mL

 

ferCD8A-ferret-spleen immunohistochemistry    

Immunochemical staining of ferret CD8A in ferret spleen with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).  
Direct ELISA : This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Ferret CD8A. The detection limit for Ferret CD8A is approximately 0.00975 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CD8a Antibody Related Products & Topics

Related Areas:

Immunology>>Cluster of Differentiation>>CD8a

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD8a Human CD8a Protein, Recombinant 10980-H08H
CD8a Mouse CD8a Protein, Recombinant 50389-M08H
CD8a Ferret CD8a Protein, Recombinant 60001-F08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD8a
WB, ELISA CD8a Antibody, Mouse Mab 10980-MM04
Mouse
CD8a
WB, ELISA Rabbit Polyclonal Antibody 50389-RP01
Mouse
CD8a
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 50389-RP02
Mouse
CD8a
WB, ELISA CD8a Antibody, Rabbit MAb 50389-R012
Mouse
CD8a
FCM CD8a Antibody ( FITC ) 50389-R208-F
Ferret
CD8a
WB, ELISA CD8a Antibody 60001-MM02
Ferret
CD8a
ELISA, IHC-P CD8a Antibody (Antigen Affinity Purified) 60001-RP02

CD8a Antibody Background

T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

References

  1. Devine, L. et al., 2000, J Immunol. 164 (2): 833-8.
  2. Arcaro, A. et al., 2000, J Immunol. 165 (4): 2068-76.
  3. Saha, K. et al., 2001, Nat Med. 7 (1): 65-72.
  4. Romero, P. et al., 2005, Eur J Immunol. 35 (11): 3092-4.
 

 

Primary Antibody Products

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"