All CD86 reagents are produced in house and quality controlled, including 24 CD86 Antibody, 4 CD86 ELISA, 48 CD86 Gene, 1 CD86 IPKit, 8 CD86 Lysate, 8 CD86 Protein, 3 CD86 qPCR. All CD86 reagents are ready to use.
Recombinant CD86 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His, C-human IgG1-Fc & His.
CD86antibodies are validated with different applications, which are ELISA, FCM, ELISA(Cap), ELISA(Det), WB, IP, IHC-P.
CD86cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD86 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD86ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.
Immune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: IP Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets