Anti-CD86 Antibody

Cat: 50068-RP01
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All CD86 Reagents
Anti-CD86 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD86 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse CD86
Recombinant Mouse CD86 protein (Catalog#50068-M08H)
Produced in rabbits immunized with purified, recombinant Mouse CD86 extracellular domain (rM CD86; Catalog#50068-M08H; NP_062261.3; Met 1-Glu 245). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD86 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD86 Antibody Alternative Names
Anti-B7 Antibody;Anti-B7-2 Antibody;Anti-B7.2 Antibody;Anti-B70 Antibody;Anti-Cd28l2 Antibody;Anti-CLS1 Antibody;Anti-ETC-1 Antibody;Anti-Ly-58 Antibody;Anti-Ly58 Antibody;Anti-MB7 Antibody;Anti-MB7-2 Antibody;Anti-TS/A-2 Antibody
CD86 Background Information

CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD86 antigen
  • Chen YQ, et al. (2006) CD28/CTLA-4--CD80/CD86 and ICOS--B7RP-1 costimulatory pathway in bronchial asthma. Allergy. 61(1): 15-26.
  • Rau FC, et al. (2009) B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion. J Immunol. 183(12): 7661-71.
  • Dai ZS, et al. (2009) Defective expression and modulation of B7-2/CD86 on B cells in B cell chronic lymphocytic leukemia. Int J Hematol. 89(5): 656-63.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 90270-RP01
    Anti-CD86 Antibody Rabbit Monoclonal ELISA 90270-R021
    Anti-CD86 Antibody Mouse Monoclonal ELISA(Cap) 80025-MM12
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 80025-T16
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 80025-RP02
    Anti-CD86 Antibody (PE) Mouse Monoclonal FCM 80025-MM10-P
    Anti-CD86 Antibody Mouse Monoclonal ELISA(Det),FCM 80025-MM10
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 80025-RP01
    Anti-CD86 Antibody Mouse Monoclonal ELISA 80025-MM04
    Anti-CD86 Antibody Rabbit Monoclonal ELISA 50068-R003
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 50068-T16
    Anti-CD86 Antibody Rabbit Polyclonal WB,ELISA,IP 50068-RP02
    Anti-CD86 Antibody (PerCP) Mouse Monoclonal FCM 10699-MM06-C
    Anti-CD86 Antibody (FITC) Mouse Monoclonal FCM 10699-MM06-F
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 10699-RP02
    Anti-CD86 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10699-R118
    Anti-CD86 Antibody Rabbit Monoclonal ELISA(Cap) 10699-R103
    Anti-CD86 Antibody (APC) Mouse Monoclonal FCM 10699-MM06-A
    Anti-CD86 Antibody Rabbit Monoclonal IHC-P 10699-R269
    Anti-CD86 Antibody Mouse Monoclonal ELISA 10699-MM02
    Anti-CD86 Antibody (PE) Mouse Monoclonal FCM 10699-MM06-P
    Anti-CD86 Antibody Mouse Monoclonal FCM 10699-MM06
    Anti-CD86 Antibody Rabbit Polyclonal ELISA 10699-RP01
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