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Product Catalog
> CD84 Protein & Antibody (SLAMF5) CD84 Protein & Antibody (SLAMF5)
Cluster of Differentiation 84 (Signaling Lymphocyte Activation Molecule 5)
CD84 Products
CD84 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD84/SLAMF5 | Human | CD84/SLAMF5 Protein, Recombinant | 10100-H08H |
| CD84/SLAMF5 | Mouse | CD84 Protein, Recombinant | 50757-M08H |
CD84 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CD84/SLAMF5 | WB, ELISA | Mouse Monoclonal Antibody | 10100-MM03 |
| Human CD84/SLAMF5 | WB, ELISA | Rabbit Monoclonal Antibody | 10100-R006 |
| Human CD84/SLAMF5 | WB, ELISA | Rabbit Polyclonal Antibody | 10100-RP01 |
| Human CD84/SLAMF5 | WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 10100-RP02 |
CD84 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD84/SLAMF5 | Human | Homo sapiens CD84/SLAMF5 cDNA Clone(NM_003874.2) | HG10100-M |
| CD84/SLAMF5 | Mouse | Mouse CD84/SLAMF5 cDNA Clone / ORF Clone | MG50757-G |
CD84 ELISA Assay Kits
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD84/SLAMF5 | Human | CD84 ELISA Pair Set, Human ELISA Pair Set |
SEK10100 |
CD84 Related Areas
Cardiovascular>>Platelet>>CD84
Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD84
Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD84
Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers / Monocyte Markers>>CD84
Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>CD84
CD84 Alternative Names
CD84, SLAMF5, DKFZp781E2378, LY9B, hCD84, mCD84 [Homo sapiens]
Cd84, CDw84, SLAMF5, A130013D22Rik [Mus musculus]
CD84 Related Products
Protein Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CD150/SLAM | Human | CD150/SLAM Protein, Recombinant |
| CD48/SLAMF2 | Human | CD48/SLAMF2 Protein, Recombinant |
| CD48/SLAMF2 | Mouse | CD48 Protein, Recombinant |
| Ly9/CD229/SLAMF3 | Mouse | LY9/CD229/SLAMF3 Protein, Recombinant |
| 2B4/CD244/SLAMF4 | Human | 2B4/CD244/SLAMF4/Fc Protein, Recombinant |
| 2B4/CD244/SLAMF4 | Human | 2B4/CD244/SLAMF4 Protein, Recombinant |
| Ly108/SLAMF6 | Human | Ly108/SLAMF6 Protein, Recombinant |
| Ly108/SLAMF6 | Mouse | Ly108/SLAMF6 Protein, Recombinant |
| CRACC/SLAMF7 | Human | CRACC/SLAMF7 Protein, Recombinant |
| CRACC/SLAMF7 | Mouse | CRACC/SLAMF7 Protein, Recombinant |
| SLAMF8 | Mouse | SLAMF8 Protein, Recombinant |
Antibody Products
Elisa Pair Set
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Mouse CRACC/SLAMF7 |
ELISA | CRACC/SLAMF7 ELISA Pair Set | SEK10100 |
cDNA Clone Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CD150/SLAM | Human | Homo sapiens CD150/SLAM cDNA Clone(NM_003037.2) |
| CD48/SLAMF2 | Human | Homo sapiens CD48/SLAMF2 cDNA Clone(NM_001778.2) |
| CD48/SLAMF2 | Mouse | Mus musculus CD48 cDNA Clone |
| Ly9/CD229/SLAMF3 | Mouse | Mus musculus LY9/CD229/SLAMF3 cDNA Clone |
| 2B4/CD244/SLAMF4 | Human | Homo sapiens 2B4/CD244/SLAMF4 cDNA Clone(NM_016382.2) |
| Ly108/SLAMF6 | Mouse | Mus musculus Ly108/SLAMF6 cDNA Clone |
| CRACC/SLAMF7 | Human | Homo sapiens CRACC/SLAMF7 cDNA Clone |
| CRACC/SLAMF7 | Mouse | Mus musculus CRACC/SLAMF7 cDNA Clone |
| SLAMF8 | Human | Homo sapiens SLAMF8 cDNA Clone |
| SLAMF8 | Mouse | Mus musculus SLAMF8 cDNA Clone |
CD84 Background
The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
CD84 Related Studies
- Martin M, et al. (2001) CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1. J Immunol. 167(7): 3668-76.
- Tangye SG, et al. (2002) CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2. Eur J Immunol. 32(6): 1640-9.
- Zaiss M, et al. (2003) CD84 expression on human hematopoietic progenitor cells. Exp Hematol. 31(9): 798-805.
- Tangye SG, et al. (2003) Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation. J Immunol. 171(5): 2485-95.
- Yan Q, et al. (2007) Structure of CD84 provides insight into SLAM family function. Proc Natl Acad Sci U S A. 104(25): 10583-8.
