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CD80 / B7-1 Antibody (FITC), Mouse MAb

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Human B7-1/CD80 Antibody Product Information
Immunogen:Recombinant Human CD80 / B7-1 Protein (Catalog#10698-H08H)
Clone ID:01
Ig Type:Mouse IgG1
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD80 / B7-1 (rh CD80 / B7-1; Catalog#10698-H08H; NP_005182.1; Met 1-Asn 242) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Human B7-1/CD80 Antibody Usage Guide
Specificity:Human CD80 / B7-1
Application:FCM
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Human B7-1/CD80 Antibody FC Application Image
CD80 / B7-1 Antibody (FITC), Mouse MAb, Flow cytometric
[Click to enlarge image]
Caption:
Profile of anti-B7-1 (CD80) reactivity on U937 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with 20 μg of human IgG/106 cells for 1 hour at 4 ℃ prior to staining, washed, then stained with FITC Mouse anti-B7-1 (CD80).
Other B7-1/CD80 Antibody Products
Reactivity: Human  
Application: FCM  
  • Slide 1
10698-MM01-50
10698-MM01-100
10698-MM01-200
50 µg 
100 µg 
200 µg 
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Reactivity: Human  
Application: ELISA  
    10698-RP01-100
    10698-RP01-200
    10698-RP01-400
    100 µg 
    200 µg 
     
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    Reactivity: Human  
    Application: ELISA  
      10698-RP02-50
      10698-RP02-100
      10698-RP02-200
      50 µg 
      100 µg 
      200 µg 
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      Reactivity: Human  
      Application: ELISA  IHC-P  
      • Slide 1
      • Slide 1
      10698-T24-100
      10698-T24-50
      10698-T24-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  WB  IHC-P  
      • Slide 1
      • Slide 1
      • Slide 1
      10698-T56-100
      10698-T56-50
      10698-T56-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  IHC-P  
      • Slide 1
      10698-R775-100
      10698-R775-50
      100 µg 
      50 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10698-MM01-P-100
      10698-MM01-P-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50446-R018-50
        50446-R018-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50446-RP01-100
          50446-RP01-200
          50446-RP01-400
          100 µg 
          200 µg 
           
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50446-RP02-50
            50446-RP02-100
            50446-RP02-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            Reactivity: Cynomolgus  
            Application: ELISA  
              90268-RP01-100
              90268-RP01-400
              90268-RP01-200
              100 µg 
               
              200 µg 
              Add to Cart
              Reactivity: Cynomolgus  
              Application: ELISA  
                90268-T16-200
                90268-T16-100
                90268-T16-50
                200 µg 
                100 µg 
                50 µg 
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                CD80/B7-1 Background

                The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.

                Human CD80/B7-1 References
              • Greenfield EA, et al. (1998) CD28/B7 costimulation: a review. Crit Rev Immunol. 18(5): 389-418.
              • Zang X, et al. (2007) The B7 family and cancer therapy: costimulation and coinhibition. Clin Cancer Res. 13(18 Pt 1): 5271-9.
              • Mir MA, et al. (2008) Signaling through CD80: an approach for treating lymphomas. Expert Opin Ther Targets. 12(8): 969-79.
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                Catalog: 10698-MM01-F-50
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                100 Tests
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                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"