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CD7 / LEU9 Antibody, Rabbit MAb

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    Mouse CD7 Antibody Product Information
    Immunogen:Recombinant Mouse CD7 protein (Catalog#50393-M08H)
    Clone ID:017
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD7 / LEU9 extracellular domain (rM CD7; Catalog#50393-M08H; NP_033984.1; Met 1-Pro 150).
    Other CD7 Antibody Products

    Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

    Lane A: NIH3T3 Whole Cell Lysate

    Lane B: Hela Whole Cell Lysate

    Lysates/proteins at 30 μg per lane.

    Secondary

    Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size:15 kDa

    Observed band size:17 kDa

    CD7 Background

    The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development.

    Mouse CD7 References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"