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CD64 / FCGR1A Antibody, Mouse MAb

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    Rat CD64/FCGR1 Antibody Product Information
    Immunogen:Recombinant Rat CD64 / FCGR1A Protein (Catalog#80016-R08H)
    Clone ID:6D4H8
    Ig Type:Mouse IgG2b
    Concentration:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD64 / FCGR1A (rR CD64 / FCGR1A; Catalog #80016-R08H; Met 1-Pro 285; NP_001094306.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
    Other CD64/FCGR1 Antibody Products
    Reactivity: Human  
    Application: ELISA  
      10256-MM06-50
      10256-MM06-100
      10256-MM06-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10256-RP01-100
        10256-RP01-200
        10256-RP01-400
        100 µg 
        200 µg 
         
        Add to Cart
        Reactivity: Human  
        Application: ELISA  WB  
        • Slide 1
        10256-RP02-50
        10256-RP02-100
        10256-RP02-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10256-T16-200
          10256-T16-50
          10256-T16-100
          200 µg 
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10256-MM09-F-50
          10256-MM09-F-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10256-MM09-P-50
          10256-MM09-P-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Mouse  
          Application: IF  ICC/IF  
          • Slide 1
          50086-R027-100
          50086-R027-50
          100 µg 
          50 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: FCM  
          • Slide 1
          50086-R027-P-100
          50086-R027-P-50
          100 Tests 
          50 Tests 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50086-RP01-100
            50086-RP01-200
            50086-RP01-400
            100 µg 
            200 µg 
             
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  WB  
            • Slide 1
            50086-RP02-50
            50086-RP02-100
            50086-RP02-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  IHC-P  
            • Slide 1
            • Slide 1
            • Slide 1
            50086-R001-50
            50086-R001-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: FCM  
            • Slide 1
            50086-R027-F-50
            50086-R027-F-100
            50 Tests 
            100 Tests 
            Add to Cart
            Reactivity: Mouse  
            Application: FCM  
            • Slide 1
            50086-R027-C-100
            50086-R027-C-50
            100 Tests 
            50 Tests 
            Add to Cart
            Reactivity: Mouse  
            Application: FCM  
            • Slide 1
            • Slide 1
            50086-R027-A-100
            50086-R027-A-50
            100 Tests 
            50 Tests 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  IHC-P  
            • Slide 1
            • Slide 1
            • Slide 1
            • Slide 1
            50086-R008-50
            50086-R008-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Rat  
            Application: FCM  
            • Slide 1
            80016-R005-F-50
            80016-R005-F-100
            50 Tests 
            100 Tests 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  
              80016-RP02-50
              80016-RP02-100
              80016-RP02-200
              50 µg 
              100 µg 
              200 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80016-R015-50
                80016-R015-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  
                  80016-RP01-400
                  80016-RP01-200
                  80016-RP01-100
                   
                  200 µg 
                  100 µg 
                  Add to Cart
                  CD64/Fc gamma RI Background

                  High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membrane glycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.

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                  Catalog: 80016-MM01-50
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                  Datasheet & Documentation

                  All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                  Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"