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CD64 / FCGR1A Antibody, Rabbit MAb

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Rat CD64/FCGR1 Antibody Product Information
Immunogen:Recombinant Rat CD64 / FCGR1A protein (Catalog#80016-R08H)
Clone ID:015
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD64 / FCGR1A (rR CD64 / FCGR1A; Catalog#80016-R08H; NP_001094306.1; Met 1-Pro 285).
Rat CD64/FCGR1 Antibody Usage Guide
Specificity:Rat CD64 / FCGR1A
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat FCGR1A. The detection limit for Rat FCGR1A is approximately 0.0049 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other CD64/FCGR1 Antibody Products
Reactivity: Human  
Application: ELISA  
    10256-MM06-50
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      10256-RP01-100
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        Reactivity: Mouse  
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          50086-R027-F-50
          50086-R027-F-100
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          Reactivity: Mouse  
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          50086-R027-C-100
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          Reactivity: Mouse  
          Application: FCM  
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          Reactivity: Mouse  
          Application: ELISA  IHC-P  
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          50086-R008-50
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          Reactivity: Rat  
          Application: FCM  
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          80016-R005-F-50
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          Reactivity: Rat  
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            Reactivity: Rat  
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              Reactivity: Rat  
              Application: ELISA  
                80016-RP01-400
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                CD64/Fc gamma RI Background

                High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membrane glycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.

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                Catalog: 80016-R015-50
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                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"