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CD64 / FCGR1 Antibody, Rabbit MAb

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Mouse CD64/FCGR1 Antibody Product Information
Immunogen:Recombinant Mouse CD64 / FCGR1 protein (Catalog#50086-M08H)
Clone ID:008
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD64 / FCGR1 (rM CD64 / FCGR1; Catalog#50086-M08H; NP_034316.1; Met 1-Pro 297).
Mouse CD64/FCGR1 Antibody Usage Guide
Specificity:Mouse CD64 / FCGR1
Has cross-reactivity in ELISA with
Mouse FCGR4
Mouse FCGR2B
Human CD16a
Human CD16b
Human CD32a
Human CD32b
Human CD64
Mouse FCGR3
Application:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse FCGR1.

IHC-P: 10-30 μg/mL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse CD64/FCGR1 Antibody IHC Application Image
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Caption:
Immunochemical staining of human GP73 in human stomach with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections).
GOLM1 / GP73 Antibody, Mouse MAb, Immunohistochemistry
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Caption:
Immunochemical staining of mouse FCGR1 in mouse liver with rabbit monoclonal antibody (10 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to Kupffer cell.
CD64 / FCGR1 Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of mouse FCGR1 in mouse brain with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to microglia.
CD64 / FCGR1 Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of mouse FCGR1 in mouse spleen with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to Kupffer cell.
CD64 / FCGR1 Antibody, Rabbit MAb, Immunohistochemistry
Other CD64/FCGR1 Antibody Products
CD64/FCGR1 Background

High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membrane glycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.

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Catalog: 50086-R008-50
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All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"