Anti-CD6 Antibody

Cat: 50711-RP01
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All CD6 Reagents
Anti-CD6 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD6 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse CD6
Recombinant Mouse CD6 protein (Catalog#50711-M08H)
Produced in rabbits immunized with purified, recombinant Mouse CD6 (rM CD6; Catalog#50711-M08H; Q91WN5; Met 1-Val 243). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD6 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

CD6 Background Information

T-cell differentiation antigen CD6, also known as TP120 and CD6, is a single-pass type I membrane protein which contains three SRCR domains. CD6 / TP120 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP120 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP120 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP120 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.

Full Name
CD6 molecule
  • Joo YS. et al., 2000, Arthritis Rheum. 43 (2): 329-35.
  • Singer NG. et al., 2002, Int Immunol. 14 (6): 585-97.
  • Gimferrer I. et al., 2005, J Immunol. 175 (3): 1406-14.
  • Alonso R. et al., 2010, J Autoimmun. 35 (4): 336-41.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD6 Antibody (PE) Mouse Monoclonal FCM 80311-MM01-P
    Anti-CD6 Antibody (FITC) Mouse Monoclonal FCM 80311-MM01-F
    Anti-CD6 Antibody Mouse Monoclonal ELISA,IHC-P 80311-MM03
    Anti-CD6 Antibody Mouse Monoclonal FCM 80311-MM01
    Anti-CD6 Antibody (APC) Mouse Monoclonal FCM 80311-MM01-A
    Anti-CD6 Antibody Rabbit Polyclonal ELISA,IHC-P 80311-T24
    Anti-CD6 Antibody Rabbit Polyclonal ELISA 50711-RP02
    Anti-CD6 Antibody (APC) Rabbit Monoclonal FCM 50711-R021-A
    Anti-CD6 Antibody Rabbit Monoclonal FCM 50711-R021
    Anti-CD6 Antibody Rabbit Monoclonal ELISA(Det) 50711-R002
    Anti-CD6 Antibody (PerCP) Rabbit Monoclonal FCM 50711-R021-C
    Anti-CD6 Antibody (PE) Rabbit Monoclonal FCM 50711-R021-P
    Anti-CD6 Antibody Rabbit Monoclonal ICC/IF,IF 50711-R001
    Anti-CD6 Antibody Rabbit Polyclonal ELISA 50711-T16
    Anti-CD6 Antibody Rabbit Monoclonal ELISA 50711-R309
    Anti-CD6 Antibody Rabbit Monoclonal ELISA(Cap) 50711-R039
    Anti-CD6 Antibody (FITC) Rabbit Monoclonal FCM 50711-R021-F
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