Anti-CD5L Antibody

Cat: 50020-R038
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Anti-CD5L Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-CD5L Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD5L
Immunogen
Recombinant Mouse CD5L protein (Catalog#50020-M08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD5L / Aim (rM CD5L; Catalog#50020-M08H; Met 1-Val 352; NP_033820.2) .
Source
Monoclonal Rabbit IgG Clone #38
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD5L Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD5L Antibody Alternative Names
Anti-42010 Antibody;Anti-AAC-11 Antibody;Anti-AI047839 Antibody;Anti-Api6 Antibody;Anti-CT2 Antibody;Anti-Pdp Antibody;Anti-Sp-alpha Antibody
CD5L Background Information

CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

Full Name
CD5 molecule-like
References
  • Resnick, D. et al., 1994, Trends Biochem. Sci. 19: 5-8.
  • Gebe, J. A. et al., 1997, J. Biol. Chem. 272 (10): 6151–6158.
  • Sarrias, M.R. et al., 2004, Crit. Rev. Immunol. 24: 1-37.
  • Mukhopadhyay, S. and Gordon, S., 2004, Immunobiology 209: 39-49.
  • Sarrias, M. R. et al.,2005, J. Biol. Chem. 280 (42): 35391–35398.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD5L Antibody Rabbit Polyclonal ELISA 50020-RP02
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    Anti-CD5L Antibody Rabbit Polyclonal ELISA,IHC-P 50020-T24
    Anti-CD5L Antibody Rabbit Monoclonal ELISA(Cap) 50020-R054
    Anti-CD5L Antibody Rabbit Monoclonal ELISA 50020-R203
    Anti-CD5L Antibody Rabbit Monoclonal ELISA 50020-R257
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