All CD53 reagents are produced in house and quality controlled, including 7 CD53 Antibody, 52 CD53 Gene, 2 CD53 IPKit, 3 CD53 Lysate, 3 CD53 Protein, 3 CD53 qPCR. All CD53 reagents are ready to use.
Recombinant CD53 proteins are expressed by HEK293 Cells with fusion tags as N-His, N-mouse IgG1-Fc.
CD53antibodies are validated with different applications, which are ELISA, WB, IP.
CD53cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD53 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: HEK293 Cells
CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.