All CD5 reagents are produced in house and quality controlled, including 40 CD5 Antibody, 1 CD5 ELISA, 52 CD5 Gene, 1 CD5 IPKit, 4 CD5 Lysate, 4 CD5 Protein, 3 CD5 qPCR. All CD5 reagents are ready to use.
Recombinant CD5 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc.
CD5antibodies are validated with different applications, which are FCM, ICC/IF, IF, WB, ELISA, IHC-P, IP, ELISA(Cap).
CD5cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD5 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD5ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.