Anti-CD5 Antibody

Cat: 11027-MM05
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All CD5 Reagents
Anti-CD5 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-CD5 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human CD5
Immunogen
Recombinant Human CD5 protein (Catalog#11027-H08H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD5 (rh CD5; Catalog#11027-H08H; NP_055022.2; Met 1-Pro 372). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #6B1C3A7
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD5 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD5 Antibody Alternative Names
Anti-LEU1 Antibody;Anti-T1 Antibody
CD5 Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.

Full Name
CD5 molecule
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters. 134 (2): 104-12.
  • Kirchgessner H, et al. (2001) The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. J Exp Med. 193 (11): 1269-84.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD5 Antibody Mouse Monoclonal FCM 80374-MM01
    Anti-CD5 Antibody Rabbit Monoclonal ELISA 80374-R006
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    Anti-CD5 Antibody (PE) Mouse Monoclonal FCM 80374-MM06-P
    Anti-CD5 Antibody Mouse Monoclonal ELISA 80374-MM03
    Anti-CD5 Antibody (FITC) Mouse Monoclonal FCM 80374-MM06-F
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    Anti-CD5 Antibody Rabbit Polyclonal ELISA 80374-RP01
    Anti-CD5 Antibody Rabbit Polyclonal ELISA,IHC-P 80374-T24
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    Anti-CD5 Antibody Rabbit Monoclonal ELISA(Cap) 50403-R101
    Anti-CD5 Antibody Rabbit Monoclonal ELISA 50403-R105
    Anti-CD5 Antibody (APC) Rabbit Monoclonal FCM 50403-R114-A
    Anti-CD5 Antibody (PerCP) Rabbit Monoclonal FCM 50403-R114-C
    Anti-CD5 Antibody (PE) Rabbit Monoclonal FCM 50403-R114-P
    Anti-CD5 Antibody Rabbit Monoclonal FCM 50403-R249
    Anti-CD5 Antibody (FITC) Rabbit Monoclonal FCM 50403-R249-F
    Anti-CD5 Antibody (PE) Rabbit Monoclonal FCM 50403-R249-P
    Anti-CD5 Antibody (APC) Rabbit Monoclonal FCM 50403-R249-A
    Anti-CD5 Antibody (FITC) Rabbit Monoclonal FCM 50403-R114-F
    Anti-CD5 Antibody Rabbit Monoclonal ELISA 11027-R322
    Anti-CD5 Antibody (PE) Rabbit Monoclonal FCM 11027-R028-P
    Anti-CD5 Antibody (FITC) Rabbit Monoclonal FCM 11027-R039-F
    Anti-CD5 Antibody Rabbit Monoclonal FCM 11027-R028
    Anti-CD5 Antibody Rabbit Monoclonal ELISA,FCM 11027-R039
    Anti-CD5 Antibody Rabbit Polyclonal WB,ELISA,IHC-P 11027-T56
    Anti-CD5 Antibody (APC) Rabbit Monoclonal FCM 11027-R028-A
    Anti-CD5 Antibody (PerCP) Rabbit Monoclonal FCM 11027-R028-C
    Anti-CD5 Antibody (PerCP) Rabbit Monoclonal FCM 11027-R039-C
    Anti-CD5 Antibody Rabbit Monoclonal WB 11027-R505
    Anti-CD5 Antibody (PE) Rabbit Monoclonal FCM 11027-R039-P
    Anti-CD5 Antibody (FITC) Rabbit Monoclonal FCM 11027-R028-F
    Anti-CD5 Antibody Rabbit Polyclonal WB,ELISA 11027-RP01
    Anti-CD5 Antibody (APC) Rabbit Monoclonal FCM 11027-R039-A
    Anti-CD5 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 11027-RP02
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