Anti-CD48 Antibody (FITC)

Cat: 50415-R341-F
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Anti-CD48 Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Product name
Anti-CD48 Antibody (FITC)
Validated applications
FCM
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD48
Immunogen
Recombinant Mouse CD48 protein (Catalog#50415-M08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48 / SLAMF2 (rM CD48 / SLAMF2; Catalog#50415-M08H; NP_031675.1; Met 1-Arg 216) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Source
Monoclonal Rabbit IgG Clone #341
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
FITC
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-CD48 Antibody (FITC) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD48 Antibody (FITC) (Rabbit Monoclonal antibody) Images
Mouse CD48/Blast-1 Flow Cytometry (FC) 5369
Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 (Cat. No. 553141) and stained with PerCP-conjugated anti-Mouse CD48 (50415-R341-C). The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
Anti-CD48 Antibody (FITC) Alternative Names
Anti-AI449234 Antibody;Anti-AW610730 Antibody;Anti-Bcm-1 Antibody;Anti-BCM1 Antibody;Anti-BLAST Antibody;Anti-BLAST-1 Antibody;Anti-BLAST1 Antibody;Anti-MEM-102 Antibody;Anti-Sgp-60 Antibody;Anti-SLAMF2 Antibody
CD48 Background Information

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD48 molecule
References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD48 Antibody (PE) Rabbit Monoclonal FCM 80286-R002-P
    Anti-CD48 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 80286-T52
    Anti-CD48 Antibody (FITC) Rabbit Monoclonal FCM 80286-R002-F
    Anti-CD48 Antibody (APC) Rabbit Monoclonal FCM 80286-R002-A
    Anti-CD48 Antibody Rabbit Monoclonal ELISA 80286-R001
    Anti-CD48 Antibody Rabbit Monoclonal FCM 80286-R002
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 80286-RP01
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 50415-RP01
    Anti-CD48 Antibody Rabbit Monoclonal ELISA(Cap) 50415-R405
    Anti-CD48 Antibody (APC) Rabbit Monoclonal FCM 50415-R341-A
    Anti-CD48 Antibody (PE) Rabbit Monoclonal FCM 50415-R341-P
    Anti-CD48 Antibody (PerCP) Rabbit Monoclonal FCM 50415-R341-C
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 50415-RP02
    Anti-CD48 Antibody Rabbit Monoclonal ELISA(Det),FCM,ICC/IF,IF 50415-R341
    Anti-CD48 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10797-R007
    Anti-CD48 Antibody Mouse Monoclonal ELISA(Cap) 10797-MM02
    Anti-CD48 Antibody (PE) Rabbit Monoclonal FCM 10797-R248-P
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 10797-RP01
    Anti-CD48 Antibody (FITC) Rabbit Monoclonal FCM 10797-R248-F
    Anti-CD48 Antibody Mouse Monoclonal ELISA 10797-MM03
    Anti-CD48 Antibody (APC) Rabbit Monoclonal FCM 10797-R248-A
    Anti-CD48 Antibody Rabbit Polyclonal WB,ELISA,IP 10797-RP04
    Anti-CD48 Antibody Rabbit Monoclonal FCM 10797-R248
    Anti-CD48 Antibody Mouse Monoclonal ELISA(Cap) 10797-MM04
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