Anti-CD48 Antibody

Cat: 10797-RP04
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Anti-CD48 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD48 Antibody
Validated applications
WB,ELISA,IP
Species reactivity
Reacts with: Human
Specificity
Human CD48
Immunogen
Recombinant Human CD48 protein (Catalog#10797-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human CD48 (rh CD48; Catalog#10797-H08H; NP_001769.2; Met 1-Ser 220). CD48 specific IgG was purified by human CD48 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD48 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:1000  
ELISA 1:5000-1:10000  
IP 0.2-1 μL/mg of lysate  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD48 Antibody (Rabbit Polyclonal antibody) Images
Human CD48/Blast-1 Immunoprecipitation(IP) 8021

CD48 was immunoprecipitated using:

Lane A:0.5 mg Raji Whole Cell Lysate

0.5 µL anti-CD48 rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose.

Primary antibody:

Anti-CD48 rabbit polyclonal antibody,at 1:500 dilution

Secondary antibody:

Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution

Developed using the odssey technique.

Performed under reducing conditions.

Predicted band size: 28 kDa

Observed band size: 37 kDa

Human CD48/Blast-1 Western blot (WB) 13280

Anti-CD48 rabbit polyclonal antibody at 1:500 dilution

Lane A: MCF7 Membrane Lysate

Lysates/proteins at 20 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:28 kDa

Observed band size:37 kDa

Anti-CD48 Antibody Alternative Names
Anti-BCM1 Antibody;Anti-BLAST Antibody;Anti-Blast-1 Antibody;Anti-BLAST1 Antibody;Anti-hCD48 Antibody;Anti-mCD48 Antibody;Anti-MEM-102 Antibody;Anti-SLAMF2 Antibody
CD48 Background Information

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD48 molecule
References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 80286-RP01
    Anti-CD48 Antibody (FITC) Rabbit Monoclonal FCM 80286-R002-F
    Anti-CD48 Antibody (APC) Rabbit Monoclonal FCM 80286-R002-A
    Anti-CD48 Antibody Rabbit Monoclonal FCM 80286-R002
    Anti-CD48 Antibody Rabbit Monoclonal ELISA 80286-R001
    Anti-CD48 Antibody (PE) Rabbit Monoclonal FCM 80286-R002-P
    Anti-CD48 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 80286-T52
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 50415-RP01
    Anti-CD48 Antibody (PE) Rabbit Monoclonal FCM 50415-R341-P
    Anti-CD48 Antibody Rabbit Monoclonal ELISA(Cap) 50415-R405
    Anti-CD48 Antibody Rabbit Monoclonal ELISA(Det),FCM,ICC/IF,IF 50415-R341
    Anti-CD48 Antibody (APC) Rabbit Monoclonal FCM 50415-R341-A
    Anti-CD48 Antibody (FITC) Rabbit Monoclonal FCM 50415-R341-F
    Anti-CD48 Antibody (PerCP) Rabbit Monoclonal FCM 50415-R341-C
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 50415-RP02
    Anti-CD48 Antibody Mouse Monoclonal ELISA(Cap) 10797-MM02
    Anti-CD48 Antibody (APC) Rabbit Monoclonal FCM 10797-R248-A
    Anti-CD48 Antibody Rabbit Polyclonal ELISA 10797-RP01
    Anti-CD48 Antibody Mouse Monoclonal ELISA(Cap) 10797-MM04
    Anti-CD48 Antibody (PE) Rabbit Monoclonal FCM 10797-R248-P
    Anti-CD48 Antibody (FITC) Rabbit Monoclonal FCM 10797-R248-F
    Anti-CD48 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10797-R007
    Anti-CD48 Antibody Mouse Monoclonal ELISA 10797-MM03
    Anti-CD48 Antibody Rabbit Monoclonal FCM 10797-R248
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