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Rat CD48 / SLAMF2 / BCM1 Protein (His Tag)
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Rat CD48 / SLAMF2 / BCM1 Protein (His Tag) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
80286-R08H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Cd48 molecule Protein Datasheet

 

CD48 / BCM1 / SLAMF2 Protein Price Inquiry ( Available Sizes )

CD48 / BCM1 / SLAMF2 Protein Product Information

Synonym : CD48, Bcm-1
Protein Construction:

A DNA sequence encoding the rat CD48 (P10252)(Met1-Arg216) was expressed, fused with a polyhistidine tag at the C-terminus.

Source: Rat
Expression Host: Human Cells

CD48 / BCM1 / SLAMF2 Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

CD48 / BCM1 / SLAMF2 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Phe 23
Molecular Mass:

The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of  the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

CD48 / BCM1 / SLAMF2 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CD48 / BCM1 / SLAMF2 Protein Related Products & Topics

Related Areas:

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hematopoietic Stem Cell Marker>>CD48/SLAMF2

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD48/SLAMF2

Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Other>>CD48/SLAMF2

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD48/SLAMF2 Human CD48/SLAMF2 Protein, Recombinant 10797-H08H
CD48/SLAMF2 Mouse CD48 Protein, Recombinant 50415-M08H
CD48/SLAMF2 Rat CD48 / BCM1 / SLAMF2 Protein, Recombinant 80286-R02H
CD48/SLAMF2 Rat CD48 / BCM1 / SLAMF2 Protein, Recombinant 80286-R08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD48/SLAMF2
WB Mouse Monoclonal Antibody 10797-MM02
Human
CD48/SLAMF2
ELISA CD48 / BCM1 / SLAMF2 Antibody 10797-MM03
Human
CD48/SLAMF2
ELISA Rabbit Polyclonal Antibody 10797-RP01
Human
CD48/SLAMF2
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10797-RP04
Human
CD48/SLAMF2
ELISA CD48 / SLAMF2 Antibody 10797-R007
Human
CD48/SLAMF2
WB CD48 / SLAMF2 Antibody 10797-R009
Human
CD48/SLAMF2
WB, FCM CD48 / SLAMF2 Antibody ( FITC ) 10797-R248-F
Mouse
CD48/SLAMF2
WB, ELISA CD48/SLAMF2 Antibody, Rabbit PAb 50415-RP01
Mouse
CD48/SLAMF2
WB, ELISA CD48/SLAMF2 Antibody, Rabbit PAb (Antigen Affinity Purified) 50415-RP02
Mouse
CD48/SLAMF2
WB, FCM CD48 / SLAMF2 Antibody ( FITC ) 50415-R341-F

CD48 / BCM1 / SLAMF2 Protein Description

CD48, also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 has a striking array of biological functions, among them adhesion, pathogen recognition, cellular activation, and cytokine regulation. CD48 performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. In rodents, CD48 is the ligand for CD2 whereas in humans, CD58 is the ligand for CD2. CD48 has a high degree of sequence homology to CD58 (LFA-3), and Mouse CD48 shares approximately 50% aa sequence identity with human CD48.

References

  1. Wong YW. et al., 1990, J Exp Med. 171: 2115-30.
  2. Ianelli CJ. et al., 1997, J Immunol. 159 (8): 3910-20.
  3. Ianelli CJ. et al., 1998, J Biol Chem. 273: 23367-75.
  4. Loertscher, R. et al., 2002, Transpl Immunol. 9: 93-6.
  5. Assarsson E. et al., 2005, J Immunol. 175: 2045-9.
  6. Bhat R. et al., 2006, J Leukocyte Biol. 79: 417-24.
  7. Munitz A. et al., 2007, Recent Pat Inflamm Allergy Drug Discov. 1 (1): 9-12.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"