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Rat CD48 / SLAMF2 / BCM1 Protein (Fc Tag)

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Rat CD48 Protein Product Information
Synonym:CD48, Bcm-1
Protein Construction:A DNA sequence encoding the rat CD48 (P10252) (Met1-Arg216) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Rat CD48 Protein QC Testing
Purity:> 95 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Phe 23
Molecule Mass:The recombinant rat CD48/Fc is a disulfide-linked homodimer. The reduced monomer comprises 435 amino acids and has a predicted molecular mass of 49.5 kDa. The apparent molecular mass of the protein is approximately 38-44 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Rat CD48 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Rat CD48 Protein SDS-PAGE
Rat CD48 / SLAMF2 / BCM1 Protein (Fc Tag) SDS-PAGE

CD48 Related Pathways

    Other CD48 Recombinant Protein Products
    CD48/Blast-1 Background

    Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

    Rat CD48/Blast-1 References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
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    Size / Price
    Catalog: 80286-R02H-50
    List Price: 
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    50 µg
    100 µg
    AvailabilityIn Stock
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    • Rat CD48 / SLAMF2 / BCM1 Protein (Fc Tag) SDS-PAGE
      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.