Anti-CD47 Antibody

Cat: 80305-RP01
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All CD47 Reagents
Anti-CD47 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD47 Antibody
Validated applications
Species reactivity
Reacts with: Rat
Rat CD47
Recombinant Rat CD47 protein (Catalog#80305-R08H)
Produced in rabbits immunized with purified, recombinant Rat CD47 (rR CD47; Catalog#80305-R08H; P97829-1; Met1-Lys140). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD47 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

CD47 Background Information

CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD47 molecule
  • Brown EJ, et al. (2001) Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 11(3): 130-5.
  • Oldenborg PA. (2004) Role of CD47 in erythroid cells and in autoimmunity. Leuk Lymphoma. 45(7): 1319-27.
  • Kaczorowski DJ, et al. (2007) Targeting CD47: NO limit on therapeutic potential. Circ Res. 100(5): 602-3.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD47 Antibody Mouse Monoclonal ELISA 80305-MM08
    Anti-CD47 Antibody Rabbit Polyclonal WB,ELISA 80305-T48
    Anti-CD47 Antibody Rabbit Polyclonal IHC-P 101928-T08
    Anti-CD47 Antibody Rabbit Polyclonal ELISA 57231-T16
    Anti-CD47 Antibody (FITC) Mouse Monoclonal FCM 12283-MM07-F
    Anti-CD47 Antibody Mouse Monoclonal FCM 12283-MM07
    Anti-CD47 Antibody Rabbit Polyclonal ELISA 12283-RP01
    Anti-CD47 Antibody Mouse Monoclonal ELISA 12283-MM01
    Anti-CD47 Antibody (PE) Mouse Monoclonal FCM 12283-MM07-P
    Anti-CD47 Antibody Rabbit Monoclonal ELISA 12283-R001
    Anti-CD47 Antibody Rabbit Monoclonal ELISA 12283-R006
    Anti-CD47 Antibody Rabbit Polyclonal ELISA 12283-T16
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