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CD46 Antibody, Mouse MAb

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Human CD46 Antibody Product Information
Immunogen:Recombinant Human CD46 protein (Catalog#12239-H08H)
Clone ID:1E3D1
Ig Type:Mouse IgG1
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; Catalog#12239-H08H; EAW93471.1; Met 1-Asp 328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Human CD46 Antibody Usage Guide
Specificity:Human CD46
No cross-reactivity in ELISA with
Human cell lysate (293 cell line)
Application:ELISA

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CD46. The detection limit for Human CD46 is approximately 0.078 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other CD46 Antibody Products
Reactivity: Human  
Application: ELISA  IHC-P  
  • Slide 1
12239-R001-50
12239-R001-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  IF  ICC/IF  
  • Slide 1
  • Slide 1
12239-MM05-100
12239-MM05-50
12239-MM05-200
100 µg 
50 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IHC-P  IP  
  • Slide 1
  • Slide 1
  • Slide 1
12239-RP02-200
12239-RP02-50
12239-RP02-100
200 µg 
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
  • Slide 1
12239-MM05-F-50
12239-MM05-F-100
50 Tests 
100 Tests 
Add to Cart
Reactivity: Human  
Application: ELISA  
    12239-RP01-100
    12239-RP01-200
    12239-RP01-400
    100 µg 
    200 µg 
     
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    12239-MM05-P-100
    12239-MM05-P-50
    100 Tests 
    50 Tests 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    12239-MM05-A-100
    12239-MM05-A-50
    100 Tests 
    50 Tests 
    Add to Cart
    CD46 Background

    CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 50% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types.

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    Catalog: 12239-MM01-200
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    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"