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CD40 Protein & Antibody (TNFRSF5)

Cluster of Differentiation 40 (Tumor Necrosis Factor Receptor Superfamily Member 5)

CD40 Products

CD40 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD40/TNFRSF5 Human CD40/TNFRSF5/ Fc Protein, Recombinant 10774-H03H
CD40/TNFRSF5 Human CD40/TNFRSF5 Protein, Recombinant 10774-H08H
CD40/TNFRSF5 Mouse CD40/TNFRSF5 Protein, Recombinant 50324-M03H
CD40/TNFRSF5 Rat CD40 / TNFRSF5 Protein, Recombinant 80151-R02H
CD40/TNFRSF5 Rat TNFRSF5 / CD40 Protein, Recombinant 80151-R08H
CD40/TNFRSF5 Cynomolgus TNFRSF5 / CD40 Protein, Recombinant 90097-C02H
CD40/TNFRSF5 Cynomolgus TNFRSF5 / CD40 Protein, Recombinant 90097-C08H

  10774-H03H:  Immobilized recombinant human CD40 at 2 µg/ml (100 µl/well) can bind biotinylated human CD40L with a linear range of 7.8-125 ng/ml. Measured by its binding ability in a functional ELISA.

  10774-H08H:  Immobilized recombinant human CD40 at 2 µg/ml (100 µl/well) can bind biotinylated human CD40L with a linear range of 15.6-500 ng/ml. Measured by its binding ability in a functional ELISA.

  50324-M03H  Measured by its ability to bind recombinant human CD40L in a functional ELISA.

CD40 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD40/TNFRSF5
WB, FCM CD40 / TNFRSF5 Antibody ( FITC ) 10774-MM03-F
Human
CD40/TNFRSF5
WB, ELISA Mouse Monoclonal Antibody 10774-MM05
Human
CD40/TNFRSF5
WB, ELISA CD40/TNFRSF5 Antibody, Rabbit MAb 10774-R004
Human
CD40/TNFRSF5
WB, ELISA Rabbit Polyclonal Antibody 10774-RP01
Human
CD40/TNFRSF5
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10774-RP02

CD40 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No

CD40/TNFRSF5
Human CD40 / TNFRSF5 cDNA Clone / ORF Clone HG10774-M

CD40/TNFRSF5
Rat CD40/TNFRSF5 cDNA Clone / ORF Clone RG80151-G

CD40/TNFRSF5
Cynomolgus CD40 cDNA Clone / ORF Clone CG90096-G

CD40 ELISA Kit

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD40/TNFRSF5
ELISA CD40/TNFRSF5 ELISA Kit SEK10774

CD40 Alternative Names

CD40, TNFRSF5, Bp50, CDW40, MGC9013, p50 [Homo sapiens]

Cd40, Tnfrsf5, RP23-428M13.1, AI326936, Bp50, GP39, HIGM1, IGM, IMD3, T-BAM, TRAP, p50 [Mus musculus]

CD40 Related Areas

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD40/TNFRSF5

Immunology>>Cytokine & Receptor>>TNF Superfamily>>CD40/TNFRSF5

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>> CD40/TNFRSF5

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers / Monocyte Markers>>CD40/TNFRSF5

Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>> CD40/TNFRSF5

CD40 Protein Related Products

Protein Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
CD120a/TNFRI /TNFRSF1A Human CD120a/Fc Protein, Recombinant
CD120a/TNFRI /TNFRSF1A Human CD120a Protein, Recombinant
CD120b/TNFRII/TNFRSF1B Human CD120b Protein, Recombinant
CD120b/TNFRII/TNFRSF1B Human CD120b/Fc Protein, Recombinant
CD134/TNFRSF4 Human OX40/CD134/Fc Protein, Recombinant
CD134/TNFRSF4 Human OX40/CD134 Protein, Recombinant
CD95/APO-1/TNFRSF6 Human CD95/APO-1/TNFRSF6/Fc Protein, Recombinant
CD95/APO-1/ TNFRSF6 Human CD95/APO-1/TNFRSF6 Protein, Recombinant
CD95/APO-1/TNFRSF6 Mouse CD95/APO-1/TNFRSF6 Protein, Recombinant
CD95/APO-1/TNFRSF6 Rat CD95/APO-1/TNFRSF6 Protein, Recombinant
CD27/TNFRSF7 Human CD27/TNFRSF7/Fc Protein, Recombinant
CD27/TNFRSF7 Mouse CD27/TNFRSF7/Fc Protein, Recombinant
CD27/TNFRSF7 Mouse CD27/TNFRSF7 Protein, Recombinant
CD30/TNFRSF8 Human CD30/TNFRSF8/Fc Protein, Recombinant
CD30/TNFRSF8 Human CD30 Protein, Recombinant
CD137/4-1BB/TNFRSF9 Human 4-1BB/TNFRSF9/Fc Protein, Recombinant
CD137/4-1BB/TNFRSF9 Human CD137/4-1BB/TNFRSF9 Protein, Recombinant
CD137/4-1BB/TNFRSF9 Mouse CD137/4-1BB/TNFRSF9 Protein, Recombinant
CD261/TRAILR1/TNFRSF10A Human TRAIL R1/TNFRSF10A/CD261/Fc Protein, Recombinant
CD261/TRAILR1/TNFRSF10A Human TRAIL R1/TNFRSF10A/CD261/Fc Protein, Recombinant
CD261/TRAILR1/TNFRSF10A Human TRAIL R1/TNFRSF10A/CD261 Protein, Recombinant
CD262/TRAILR2/TNFRSF10B Human TRAILR2/Fc Protein, Recombinant
CD262/TRAILR2/TNFRSF10B Human TRAILR2 Protein, Recombinant
CD262/TRAILR2/TNFRSF10B Mouse TRAILR2/Fc Protein, Recombinant
CD262/TRAILR2/TNFRSF10B Mouse TRAILR2 Protein, Recombinant
CD264/TRAILR4/TNFRSF10D Human TRAILR4/Fc Protein, Recombinant
CD264/TRAILR4/TNFRSF10D Human TRAILR4 Protein, Recombinant
CD27L/CD70/TNFSF7 Human CD70/Fc Protein, Recombinant
CD30L/TNFSF8 Human CD30L/TNFSF8/Fc Protein, Recombinant
CD137L/4-1BBL/TNFSF9 Mouse 4-1BB Ligand Protein, Recombinant
CD137L/4-1BBL/TNFSF9 Human 4-1BB/TNFRSF9/Fc Protein, Recombinant
Antibody Products
Molecule Application Description //For Detailed Info. and Price------CLICK!
Human
CD120a/TNFRI /TNFRSF1A
WB, ELISA Rabbit Monoclonal Antibody
Human
CD120a/TNFRI /TNFRSF1A
WB, ELISA Rabbit Polyclonal Antibody
Human
CD120a/TNFRI /TNFRSF1A
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human
CD134/TNFRSF4
WB, ELISA OX40/CD134 Antibody, Rabbit PAb
Human
CD134/TNFRSF4
WB, ELISA OX40/CD134 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human
CD95/APO-1/TNFRSF6
WB, ELISA CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb
Human
CD95/APO-1/TNFRSF6
WB, ELISA CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb (Antigen Affinity Purified)
Mouse
CD95/APO-1/TNFRSF6
WB, ELISA CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb
Mouse
CD95/APO-1/TNFRSF6
WB, ELISA CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb (Antigen Affinity Purified)
Mouse
CD137L/4-1BBL/TNFSF9
WB, ELISA Rabbit Monoclonal Antibody
Mouse
CD137L/4-1BBL/TNFSF9
ELISA Rabbit Polyclonal Antibody
Mouse
CD137L/4-1BBL/TNFSF9
WB, ELISA Rabbit Polyclonal Antibody
Human
CD262/TRAIL R2/TNFRSF10B
WB, ELISA Rabbit Polyclonal Antibody
Human
CD262/TRAIL R2/TNFRSF10B
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse
CD262/TRAIL R2/TNFRSF10B
WB, ELISA TRAIL R2/TNFRSF10B/CD262 Antibody, Rabbit PAb (Antigen Affinity Purified)
Mouse
CD137L/4-1BBL/TNFSF9
WB, ELISA Rabbit Monoclonal Antibody
Mouse
CD27
WB, ELISA CD27 Antibody, Rabbit PAb
Mouse
CD27
WB, ELISA CD27 Antibody, Rabbit PAb (Antigen Affinity Purified)
cDNA Clone Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
CD120a/TNFRI /TNFRSF1A Human Homo sapiens CD120a/TNFRI cDNA Clone(NM_001065.2)
CD18/TNFRSF3 Human Homo sapiens TNFRSF3 cDNA Clone(NM_002342.1)
CD134/TNFRSF4 Human Homo sapiens TNFRSF4 cDNA Clone(NM_003327.2)
CD40/TNFRSF5 Human Homo sapiens CD40/TNFRSF5 cDNA Clone(NM_001250.4)
CD95/TNFRSF6 Human Homo sapiens CD95/Fas transcript variant 1 cDNA Clone(NM_000043.3)
CD95/APO-1/TNFRSF6 Mouse Mus musculus CD95/APO-1/TNFRSF6 cDNA Clone
CD95/APO-1/TNFRSF6 Rat Rattus norvegicus CD95/APO-1/TNFRSF6 cDNA Clone
CD137/4-1BB/TNFSF9 Human Homo sapiens 4-1BB/TNFRSF9 cDNA Clone(NM_001561.4)
CD261/TRAILR1/TNFRSF10A Human Homo sapiens TRAILR1 cDNA Clone(NM_003844.2)
CD262/TRAILR2/TNFRSF10B Human Homo sapiens TRAILR2 cDNA Clone(NM_003842.3)
CD262/TRAILR2/TNFRSF10B Mouse Mus musculus TRAILR2 cDNA Clone
CD263/TRAILR3/TNFRSF10C Human Homo sapiens TRAILR3 cDNA Clone(NM_003841.2)
CD264/TRAILR4/TNFRSF10D Human Homo sapiens TRAILR4 cDNA Clone(NM_003840.3)
CD266/TNFRSF12 Human Homo sapiens TNFRSF12 cDNA Clone(NM_016639.2)
CD27/TNFRSF7 Mouse Mus musculus CD27/TNFRSF7 cDNA Clone
CD30/TNFRSF8 Human Homo sapiens CD30/TNFRSF8 cDNA Clone
CD40L/CD154/TNFSF5 Human Homo sapiens CD40L/TNFSF5 cDNA Clone(NM_000074.2)
CD95L/FASL/CD178/TNFSF6 Human Homo sapiens FasL/TNFSF6 cDNA Clone(NM_000639.1)
CD27L/CD70/TNFSF7 Human Homo sapiens CD27L/TNFSF7 cDNA Clone(NM_001252.3)
CD30L/CD153/TNFSF8 Human Homo sapiens CD30L/TNFSF8 cDNA Clone(NM_001244.2)
CD253/ TNFSF10/TRAIL Human Homo sapiens TNFSF10/TRAIL cDNA Clone(NM_003810.2)
CD256/TNFSF13 Human Homo sapiens TNFSF13 cDNA Clone(NM_003808.3)
CD257/TNFSF13B/TNFSF20 Human Homo sapiens BAFF/TNFSF13B cDNA Clone(NM_006573.3)
TNFSF13B/TNFSF20 Mouse Mus musculus BLyS/TNFSF13B cDNA Clone
CD258/ TNFSF14 Human Homo sapiens LIGHT/TNFSF14 transcript variant 1 cDNA Clone(NM_003807.2)

CD40 Background

CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.

CD40 Related Studies

  1. van Kooten C, et al. (2000). CD40-CD40 ligand. J Leukoc Biol. 67 (1): 2–17.
  2. Bhushan A, et al. (2002). CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes. Immunol Res. 24 (3): 311–24.
  3. Chatzigeorgiou A, et al. (2009) CD40/CD40L signaling and its implication in health and disease. Biofactors. 35(6): 474-83.
  4. Li R, et al. (2009) Expression of CD40 and CD40L in Gastric Cancer Tissue and Its Clinical Significance. Int J Mol Sci. 10(9): 3900-17.
  5. Lievens D, et al. (2009) The multi-functionality of CD40L and its receptor CD40 in atherosclerosis. Thromb Haemost. 102(2): 206-14.

CD40 related areas, pathways, and other information

TNF Superfamily Ligands

  • EDA-A1 / Ectodysplasin-A1*
  • TNFSF6 / CD95L / CD178*
  • TNFSF12 / TWEAK*
  • TNFSF13 / CD256*
  • TNFSF3 / TNFC / lymphotoxin beta*
  • TNFSF4*
  • TNFSF15*

TNF Receptor Superfamily

  • TNFRSF3 / CD18 / LTBR*
  • TNFRSF10C / CD263 / TRAILR3*
  • TNFRSF18*
  • TNFRSF12A / FN14 / TWEAKR*
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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