CD3D (Protein|Antibody|cDNA Clone|ELISA Kit)

All CD3D reagents are produced in house and quality controlled, including 10 CD3D Antibody, 1 CD3D ELISA, 54 CD3D Gene, 5 CD3D IPKit, 7 CD3D Lysate, 7 CD3D Protein, 3 CD3D qPCR. All CD3D reagents are ready to use.

Recombinant CD3D proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His, C-human IgG1-Fc & Flag, C-flag.

CD3D antibodies are validated with different applications, which are ELISA, WB, IP, ELISA(Cap), IHC-P, ELISA(Det).

CD3D cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD3D of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

CD3D ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

CD3D Protein (7)

CD3D Protein, Canine, Recombinant (Fc Tag)

70108-D02H

Expression host: HEK293 Cells

Canine CD3d/CD3 delta Protein 12298

CD3D Protein, Cynomolgus, Recombinant (His Tag)

90046-C08H

Expression host: HEK293 Cells

Cynomolgus CD3d/CD3 delta Protein 12759

CD3D Protein, Human, Recombinant (His Tag)

10981-H08H

Expression host: HEK293 Cells

Human CD3d/CD3 delta Protein 9269

CD3D Protein, Human, Recombinant (Fc & FLAG Tag)

10981-H23H

Expression host: HEK293 Cells

Human CD3d/CD3 delta Protein 9270

CD3D Protein, Human, Recombinant (Flag Tag)

10981-H23H-B

Expression host: HEK293 Cells

Human CD3D Protein 19992

CD3D Protein, Cynomolgus, Recombinant (Fc Tag)

90046-C02H

Expression host: HEK293 Cells

Cynomolgus CD3d/CD3 delta Protein 12758

CD3D Protein, Mouse, Recombinant (Fc Tag)

50390-M02H

Expression host: HEK293 Cells

Mouse CD3d/CD3 delta Protein 11609
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CD3D Antibody (10)

Application Clonality
Host

Anti-CD3D Antibody

10981-MM07

Specificity: Human

Application: ELISA(Cap)

Clonality: MAb

Anti-CD3D Antibody

10981-MM06

Specificity: Human

Application: IHC-P

Clonality: MAb

Human CD3d/CD3 delta Immunohistochemistry(IHC) 4510

Anti-CD3D Antibody

10981-MM12

Specificity: Human

Application: WB,IP

Clonality: MAb

Human CD3d/CD3 delta Immunoprecipitation(IP) 6175

Anti-CD3D Antibody

10981-MM16

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-CD3D Antibody

10981-R138

Specificity: Human

Application: WB,IP

Clonality: MAb

Human CD3d/CD3 delta Western blot (WB) 13313

Anti-CD3D Antibody

10981-R006

Specificity: Human

Application: WB,ELISA,IP

Clonality: MAb

Human CD3d/CD3 delta Immunoprecipitation(IP) 6176

Anti-CD3D Antibody

10981-RP02

Specificity: Human

Application: WB,ELISA,IP

Clonality: PAb

Human CD3d/CD3 delta Immunoprecipitation(IP) 8037

Anti-CD3D Antibody

102294-T32

Specificity: Mouse

Application: WB

Clonality: PAb

Mouse CD3d/CD3 delta Western blot (WB) 14661

Anti-CD3D Antibody

10981-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-CD3D Antibody

10981-MM08

Specificity: Human

Application: WB,ELISA,ELISA(Det),IP

Clonality: MAb

Human CD3d/CD3 delta Western blot (WB) 13311
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CD3D ELISA KIT & match antibody elias pair set ( 1 )

CD3D Matched ELISA Antibody Pair Set,Human

SEK10981

Assay Range: 62.5 pg/ml

Human CD3d/CD3 delta ELISA Pair Set Standard Curve 13899

CD3D cDNA Clone (54)

Canine
Rhesus
Rat
Human
Mouse

CD3D qPCR Primer (3)

CD3D IP Kit (5)

CD3D Lysate (7)

T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. The majority of T cell receptor (TCR) complexes in mice and humans consist of a heterodimer of polymorphic TCRalpha and beta chains along with invariant CD3gamma, delta, epsilon, and zeta chains. CD3 chains are present as CD3gammaepsilon, deltaepsilon, and zetazeta dimers in the receptor complex and play critical roles in the antigen receptor assembly, transport to the cell surface, and the receptor-mediated signal transduction. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). CD3D contains 1 ITAM domain and has been shown to interact with CD8A. In the mouse, knockout of CD3delta allows some degree of T lymphocyte differentiation since mature CD4 and CD8 as well as TCRgammadelta T lymphocytes are observed in the periphery. In contrast, deleterious mutation of the CD3delta encoding gene in the human leads to a severe combined immunodeficiency characterised by the complete absence of mature T cell subpopulations including TCRalpha/beta and TCRgamma/delta. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. In humans the absence of CD3 delta results in a complete arrest in thymocyte development at the stage of double negative to double positive transition and the development of gamma delta T-cell receptor-positive T cells is also impaired.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
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