All CD3G reagents are produced in house and quality controlled, including 1 CD3G Antibody, 52 CD3G Gene, 3 CD3G qPCR. All CD3G reagents are ready to use.
CD3Gantibodies are validated with different applications, which are WB.
CD3GcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD3G of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD3G gene encodes CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the TCR alpha/beta and gamma/delta heterodimers, forms the TCR-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The CD3 gamma chain has long been considered to mediate targeting to lysosomes for degradation. Defects in this gene are associated with T cell immunodeficiency. Further, it has been proposed as one of the important candidate genes for cancer development due to its pivotal roles in TCR signaling pathway.