Anti-CD38 Antibody

Cat: 50191-RP02
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All CD38 Reagents
Anti-CD38 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD38 Antibody
Validated applications
ELISA,IHC-P,FCM
Species reactivity
Reacts with: Mouse, Rat
Not React with: Human
Specificity
Mouse CD38
Immunogen
Recombinant Mouse CD38 protein (Catalog#50191-M08H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse CD38 (rM CD38; Catalog#50191-M08H; NP_031672.2; Leu 45-Thr 304). CD38 specific IgG was purified by mouse CD38 affinity chromatography .
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD38 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  
IHC-P 1:2500-1:10000  
FCM 1:25-1:100  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD38 Antibody (Rabbit Polyclonal antibody) Images
Mouse CD38/ADPRC1 Immunohistochemistry(IHC) 3343
Immunochemical staining of mouse CD38 in mouse kidney with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections). Positive staining was localized to endotheliocyte.
Mouse CD38/ADPRC1 Immunohistochemistry(IHC) 3345
Immunochemical staining of mouse CD38 in mouse heart with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections). Positive staining was localized to endotheliocyte.
Mouse CD38/ADPRC1 Flow Cytometry (FC) 5370
Flow cytometric analysis of CD38 expression on spleen lymphocytes. BALB/c splenocytes were stained with Mouse CD38 Affinity Purified Polyclonal Ab (50191-RP02), then a FITC-conjugated second step antibody. The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
Anti-CD38 Antibody Alternative Names
Anti-ADPRC 1-rs1 Antibody;Anti-ADPRC1 Antibody;Anti-Cd38 Antibody;Anti-Cd38-rs1 Antibody;Anti-I-19 Antibody
CD38 Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

Full Name
CD38 molecule
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD38 Antibody Mouse Monoclonal ELISA 65003-MM01
    Anti-CD38 Antibody Rabbit Polyclonal ELISA,IHC-P,ICC/IF,IF 80229-T26
    Anti-CD38 Antibody Rabbit Polyclonal ELISA 80229-RP01
    Anti-CD38 Antibody Rabbit Polyclonal ELISA 50191-RP01
    Anti-CD38 Antibody Rabbit Monoclonal ELISA,IHC-P 50191-R032
    Anti-CD38 Antibody Rabbit Monoclonal IHC-P 10818-R017
    Anti-CD38 Antibody Mouse Monoclonal IHC-P 10818-MM20
    Anti-CD38 Antibody Rabbit Monoclonal IHC-P 10818-R228
    Anti-CD38 Antibody Rabbit Monoclonal IHC-P 10818-R128
    Anti-CD38 Antibody (PE) Mouse Monoclonal FCM 10818-MM27-P
    Anti-CD38 Antibody Mouse Monoclonal FCM 10818-MM27
    Anti-CD38 Antibody (PE) Mouse Monoclonal FCM 10818-MM12T-P
    Anti-CD38 Antibody Rabbit Polyclonal WB,ELISA,IP 10818-RP02
    Anti-CD38 Antibody Rabbit Monoclonal ELISA(Cap) 10818-R067
    Anti-CD38 Antibody Rabbit Monoclonal ELISA 10818-R011
    Anti-CD38 Antibody Rabbit Monoclonal WB,ELISA,IP 10818-R003
    Anti-CD38 Antibody (APC) Mouse Monoclonal FCM 10818-MM27-A
    Anti-CD38 Antibody Mouse Monoclonal ELISA 10818-MM22
    Anti-CD38 Antibody Rabbit Polyclonal ELISA 10818-RP01
    Anti-CD38 Antibody Mouse Monoclonal ELISA 10818-MM31
    Anti-CD38 Antibody (FITC) Mouse Monoclonal FCM 10818-MM27-F
    Anti-CD38 Antibody (PerCP) Mouse Monoclonal FCM 10818-MM27-C
    Anti-CD38 Antibody Mouse Monoclonal ELISA 10818-MM03
    Anti-CD38 Antibody Mouse Monoclonal FCM 10818-MM12T
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