CD34 Protein & Antibody

Cluster of Differentiation 34

CD34 Protein Products

Molecule	Species	Description	Cat. No
CD34	Human	CD34/Fc Protein, Recombinant	10103-H02H
CD34	Human	CD34 Protein, Recombinant	10103-H08H
CD34	Mouse	CD34 Protein, Recombinant	50589-M08H

  10103-H02H: When 4 x 10⁴ cells/well are added to human CD34 coated plates (0.8 µg/mL, 100 µL/well) , approximately > 40 % will adhere after one hour at 37 ℃. Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line.

  10103-H08H:

1. Measured by its ability to bind human CD62L in a functional ELISA.

2. When 4 x 10⁴ cells/well are added to human CD34 coated plates (0.8 µg/mL, 100 µL/well) , approximately > 40 % will adhere after one hour at 37 ℃. Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line.

  50589-M08H: When 4 x 10⁴ cells/well are added to mouse CD34 coated plates (0.8 µg/mL, 100 µL/well) , approximately > 30 % will adhere after one hour at 37 ℃. Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line.

CD34 Antibody

Molecule	Application	Description	Cat. No
Mouse CD34	WB, ELISA	CD34 Antibody, Rabbit PAb	50589-RP01
Mouse CD34	WB, ELISA	CD34 Antibody, Rabbit PAb (Antigen Affinity Purified)	50589-RP02
Mouse CD34	WB, ELISA	CD34 Antibody	50589-R013
Mouse CD34	WB, ELISA, IHC-P	CD34 Antibody	50589-R013-F

CD34 cDNA Clone

Molecule	Species	Description	Cat. No
CD34	Human	CD34 cDNA Clone / ORF Clone	HG10103-M
CD34	Mouse	CD34 cDNA Clone / ORF Clone	MG50589-M
CD34	Rat	CD34 cDNA Clone / ORF Clone	RG80262-G

All CD34 Protein and Antibody

CD34 Alternative Names

CD34, RP11-328D5.2

CD34 Related Areas

Cardiovascular>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CD34

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hematopoietic Stem Cell Marker>>CD34

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Hemangioblast Marker>>CD34

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>CD34

Cancer>>Cancer Stem Cell (CSC)>>CD34

Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CD34

Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD34

CD34 Protein Related Products

Protein Products

Molecule	Species	Description
CD38	Human	CD38 Protein, Recombinant
CD38	Mouse	CD38 Protein, Recombinant
CD48/SLAMF2	Human	CD48 Protein, Recombinant
CD48/SLAMF2	Mouse	CD48 Protein, Recombinant
CD150/SLAM	Human	CD150/SLAM Protein, Recombinant

Antibody Products

Molecule	Application	Description
Human CD38	ELISA	Mouse Monoclonal Antibody
Human CD38	WB	Mouse Monoclonal Antibody
Human CD38	WB, ELISA	CD38 Antibody, Rabbit MAb
Human CD38	WB, ELISA	Rabbit Polyclonal Antibody
Human CD38	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse CD38	WB, ELISA	Rabbit Monoclonal Antibody
Mouse CD38	WB, ELISA	Rabbit Polyclonal Antibody
Mouse CD38	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human CD48/SLAMF2	WB	Mouse Monoclonal Antibody
Human CD48/SLAMF2	ELISA	Mouse Monoclonal Antibody
Human CD48/SLAMF2	ELISA	Rabbit Polyclonal Antibody
Human CD48/SLAMF2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse CD48/SLAMF2	WB, ELISA	CD48/SLAMF2 Antibody, Rabbit PAb
Mouse CD48/SLAMF2	WB, ELISA	CD48/SLAMF2 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human CD150/SLAM	WB, ELISA	Mouse Monoclonal Antibody
Human CD150/SLAM	WB, ELISA	Rabbit Monoclonal Antibody
Human CD150/SLAM	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human CD150/SLAM	WB, ELISA	Rabbit Polyclonal Antibody

cDNA Clone Products

Molecule	Species	Description
CD34	Human	Homo sapiens CD34 transcript variant 1 cDNA Clone(NM_001025109.1)
CD34T	Human	Homo sapiens CD34T transcript variant 2 cDNA Clone(NM_001773.2)
CD38	Human	Homo sapiens CD38 cDNA Clone(NM_001775.2)
CD38	Mouse	Mus musculus CD38 cDNA Clone
CD48/SLAMF2	Human	Homo sapiens CD48 cDNA Clone(NM_001778.2)
CD150/SLAM	Human	Homo sapiens CD150/SLAM cDNA Clone(NM_003037.2)

CD34 Background

Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. It has been widely used as a stem and progenitor cell marker, and clinical CD34+ stem cell transplantation (CD34+SCT) has been performed for tumor purging. CD34 monoclonal antibodies are widely used to identify and isolate hemopoietic progenitors and to classify acute and chronic leukemias.

CD34 Related Studies

1. Hogan CJ, et al. (2002) Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted into NOD/SCID mice. Proc Nat Acad Sci USA. 99 (1): 413–8.
2. Nielsen JS,et al. (2009) CD34 is a key regulator of hematopoietic stem cell trafficking to bone marrow and mast cell progenitor trafficking in the periphery. Microcirculation. 16(6): 487-96.
3. Mastrandrea F,et al. (2009) CD34+ hemopoietic precursor and stem cells traffic in peripheral blood of celiac patients is significantly increased but not directly related to epithelial damage severity. Eur Ann Allergy Clin Immunol. 40(3): 90-103.
4. Pasquet S,et al. (2009) Long-term benefit of intracardiac delivery of autologous granulocyte-colony-stimulating factor-mobilized blood CD34+ cells containing cardiac progenitors on regional heart structure and function after myocardial infarct. Cytotherapy. 11(8): 1002-15.li>