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CD32b/Fc gamma RIIB/FCGR2B Protein, Antibody, ELISA Kit, cDNA Clone

Rat CD32b/Fc gamma RIIB/FCGR2B Protein

Expression host: Human Cells
  • Slide 1
80018-R08H-50
80018-R08H-100
50 µg / $198
100 µg / $348
Add to Cart

Human CD32b/Fc gamma RIIB/FCGR2B Protein

Description: Active
Expression host: Human Cells
  • Slide 1
10259-H08H-50
10259-H08H-100
50 µg / $178
100 µg / $298
Add to Cart
Expression host: Human Cells
  • Slide 1
10259-H27H-50
10259-H27H-100
50 µg / $178
100 µg / $298
Add to Cart
Expression host: Human Cells
  • Slide 1
10259-H27H-B-50
10259-H27H-B-20
50 µg / $298
20 µg / $158
Add to Cart
Expression host: CHO Cells
  • Slide 1
10259-H08C-50
10259-H08C-100
50 µg / $178
100 µg / $298
Add to Cart

Cynomolgus CD32b/Fc gamma RIIB/FCGR2B Protein

Expression host: Human Cells
  • Slide 1
90014-C08H-50
90014-C08H-100
50 µg / $198
100 µg / $298
Add to Cart
Expression host: Human Cells
  • Slide 1
90014-C27H-50
90014-C27H-100
50 µg / $198
100 µg / $348
Add to Cart
Expression host: Human Cells
  • Slide 1
90014-C27H-B-50
90014-C27H-B-20
50 µg / $348
20 µg / $178
Add to Cart

CD32b/Fc gamma RIIB/FCGR2B Related Areas

CD32b/Fc gamma RIIB/FCGR2B Related Pathways

CD32b/Fc gamma RIIB/FCGR2B Related Product

    CD32b/Fc gamma RIIB/FCGR2B Summary & Protein Information

    CD32b/Fc gamma RIIB/FCGR2B Background

    Subunit structure: Isoform IIB1 interacts with measles virus N protein. N protein is released in the blood following lysis of measles infected cells. This interaction presumably block inflammatory immune response. Interacts with INPP5D/SHIP1. Interacts with FGR. Interacts with LYN.
    Domain: Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2- containing phosphatases.
    Subcellular location: Cell membrane; Single-pass type I membrane protein.
    Tissue specificity: Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
    Post-translational: Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
    Involvement in disease: Note=A chromosomal aberration involving FCGR2B is found in a follicular lymphoma. Translocation t(1;22)(q22;q11). The translocation leads to the hyperexpression of the receptor. This may play a role in the tumor progression.
    Systemic lupus erythematosus (SLE) [MIM:152700]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
    Sequence similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    General information above from UniProt

    CD32b/Fc gamma RIIB/FCGR2B Alternative Name

    CD32b/Fc gamma RIIB/FCGR2B Related Studies

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"