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CD32 Protein & Antibody (CDw32, FCGR2)

Cluster of differentiation 32 (Fc gamma Receptor II)

CD32 Alternative Names

CD32, CD32A, CD32B, FcγRII, FCGR2, FCGR2A, FCGR2B, FCG2, CDw32, IGFR2, FcGR [Homo sapiens]

CD32, FcγRII, FcgRII, Fcgr2, Fcgr2a, Fcgr2b, Ly-17, Ly-m20, LyM-1, Lym-1 [Mus musculus]

CD32 Protein & Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for Cluster of differentiation (CD) related research. We offer CD proteins from human and mouse. Our antibody products include mouse monoclonal and rabbit polyclonal antibodies for application such as ELISA, Western Blotting, IHC, etc. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

CD32 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD32/FCGR2 Mouse CD32 / FCGR2 / Fc gamma RII Protein 50030-M08H
CD32/FCGR2 Mouse CD32 / FCGR2 / Fc gamma RII Protein, with AVI Tag 50030-M27H
CD32/FCGR2 Mouse CD32 / FCGR2 / Fc gamma RII Protein, with AVI Tag, Biotinylated 50030-M27H-B
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein 10374-H02H
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA  Protein 10374-H08H
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein 10374-H08B
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein 10374-H08C
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein,with His Tag (167 Arg/His) 10374-H08H1
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein,with AVI Tag 10374-H27H
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein (167 Arg/His),with AVI Tag 10374-H27H1
CD32a/FCGR2A Human CD32a / FCGR2A  / Fc gamma RIIA Protein,with AVI Tag, Biotinylated 10374-H27H-B
CD32a/FCGR2A Human CD32a / FCGR2A / Fc gamma RIIA Protein (131 Arg/His),with AVI Tag,Biotinylated 10374-H27H1-B
CD32a/FCGR2A Cynomolgus CD32a / FCGR2A / Fc gamma RIIA Protein 90015-C08H
CD32a/FCGR2A Cynomolgus CD32a / FCGR2A / Fc gamma RIIA Protein,with AVI Tag 90015-C27H
CD32a/FCGR2A Cynomolgus CD32a / FCGR2A / Fc gamma RIIA Protein,with AVI Tag,Biotinylated 90015-C27H-B
CD32a/FCGR2A Cynomolgus CD32a / FCGR2A / Fc gamma RIIA Protein
90016-C08H
CD32b/FCGR2B Human CD32b / FCGR2B / Fc gamma RIIB Protein
10259-H08C
CD32b/FCGR2B Human CD32b / FCGR2B / Fc gamma RIIB Protein 10259-H08H
CD32b/FCGR2B Human CD32b / FCGR2B / Fc gamma RIIB Protein,with AVI Tag 10259-H27H
CD32b/FCGR2B Human CD32b / FCGR2B / Fc gamma RIIB Protein,with AVI Tag,Biotinylated 10259-H27H-B
CD32b/FCGR2B Rat CD32b / FCGR2B / Fc gamma RIIB Protein 80018-R08H
CD32b/FCGR2B Cynomolgus CD32b / FCGR2B / Fc gamma RIIB Protein 90014-C08H
CD32b/FCGR2B Cynomolgus CD32b / FCGR2B / Fc gamma RIIB Protein,with AVI Tag 90014-C27H
CD32b/FCGR2B Cynomolgus CD32b / FCGR2B / Fc gamma RIIB Protein,with AVI Tag,Biotinylated 90014-C27H-B

  10374-H08H:  Immobilized recombinant human CD32a at 10 µg/mL (100 µl/well) can bind human IgG2 with a linear range of 12.5-200 ng/ml. Measured by its binding ability in a functional ELISA.

  10374-H27H1-B:

1. Immobilized human IgG2 at 10 µg/ml (100 µl/well) can bind biotinylated human CD32 with a linear ranger of 0.16-0.8 μg/ml. Measured by its binding ability in a functional ELISA.

2. Using the Octet RED System, the affinity constant (Kd) of CD32a-AVI-His + BirA bound to human IgG was 12nM. Measured by its binding ability in a functional ELISA.

  90015-C08H: Using the Octet RED System, the affinity constant (Kd) of cynomolgus CD32A-His bound to human IgG was 5.8 μM

  10259-H08H:  Immobilized recombinant human CD32b at 10 µg/mL (100 µl/well) can bind human IgG2 with a linear range of 0.16-6.4 µg/ml. Measured by its binding ability in a functional ELISA.

CD32 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Mouse
CD32/FCGR2
WB, ELISA CD32 / FCGR2 / Fc gamma RII Antibody, Rabbit MAb 50030-R005
Mouse
CD32/FCGR2
ELISA CD32 / FCGR2 / Fc gamma RII Antibody, Rabbit PAb 50030-RP01
Mouse
CD32/FCGR2
WB, ELISA CD32 / FCGR2 / Fc gamma RII Rabbit PAb (Antigen Affinity Purified) 50030-RP02
Human
CD32a/FCGR2A
ELISA CD32a / FCGR2A / Fc gamma RII Mouse MAb 10374-MM01
Human
CD32a/FCGR2A
ELISA CD32a / FCGR2A / Fc gamma RIIA Mouse MAb 10374-MM02
Human
CD32a/FCGR2A
WB, ELISA CD32a / FCGR2A / Fc gamma RIIA Antibody 10374-MM03
Human
CD32a/FCGR2A
WB, ELISA CD32a / FCGR2A / Fc gamma RIIA Antibody 10374-RP01
Human
CD32a/FCGR2A
WB, ELISA CD32a / FCGR2A / Fc gamma RIIA Antibody (Antigen Affinity Purified) 10374-RP02
Cynomolgus
CD32a/FCGR2A
WB, ELISA CD32a / FCGR2A / Fc gamma RIIA Antibody (Antigen Affinity Purified) 90015-RP02
Cynomolgus
CD32a/FCGR2A
WB, ELISA CD32a / Fc gamma RIIA / FCGR2A Antibody (Antigen Affinity Purified) 90016-RP02
Cynomolgus
CD32a/FCGR2A
WB, ELISA CD32a / Fc gamma RIIA / FCGR2A Antibody 90016-MM01
Cynomolgus
CD32a/FCGR2A
WB, ELISA CD32a / FCGR2A / Fc gamma RIIA Antibody 90015-MM06
Human
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Mouse MAb
10259-MM02
Human
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Antibody, Rabbit Mab
10259-R112
Human
CD32b/FCGR2B
IHC CD32b / FCGR2B /Fc gamma RIIB Antibody, Rabbit Mab
10259-R110
Human
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Rabbit PAb 10259-RP01
Human
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Rabbit PAb (Antigen Affinity Purified) 10259-RP03
Rat
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Antibody 80018-RP01
Rat
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Antibody (Antigen Affinity Purified) 80018-RP02
Cynomolgus
CD32b/FCGR2B
WB, ELISA CD32b / FCGR2B / Fc gamma RIIB Rabbit PAb (Antigen Affinity Purified) 90014-RP02

CD32 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD32/FCGR2 Mouse CD32 / FCGR2 / Fc gamma RIIA cDNA Clone / ORF Clone MG50030-M
CD32a/FCGR2a Human CD32a / FCGR2A / Fc gamma RIIA transcript variant 1cDNA Clone / ORF Clone HG10374-M
CD32a/FCGR2a Rat CD32a / FCGR2A / Fc gamma RIIA cDNA Clone / ORF Clone RG80015-M
CD32a/FCGR2a Cynomolgus CD32a / FCGR2A / Fc gamma RIIA cDNA Clone / ORF Clone CG90016-M
CD32b/FCGR2B Human CD32b / FCGR2B / Fc gamma RIIB transcript variant 3 cDNA Clone / ORF Clone HG10259-M
CD32b/FCGR2B Human CD32b / FCGR2B / Fc gamma RIIB transcript variant 2 cDNA Clone / ORF Clone HG10260-M
CD32b/FCGR2B Rat CD32b / FCGR2B / Fc gamma RIIB cDNA Clone / ORF Clone RG80018-M
CD32b/FCGR2B Cynomolgus CD32b / FCGR2B / Fc gamma RIIB cDNA Clone / ORF Clone CG90014-M

CD32 ELISA Kit

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Cynomolgus CD32a/FCGR2A ELISA CD32a / Fc gamma RIIA / FCGR2A ELISA Pair Set, Cynomolgus ELISA Pair Set SEK90016
Human CD32b/FCGR2B ELISA CD32b / FCGR2B / Fc gamma RIIB ELISA Kit SEK10259
Human CD32b/FCGR2B ELISA CD32b / FCGR2B / Fc gamma RIIB ELISA Pair Set,Human ELISA Pair Set SEKA10259

CD32 Related Areas

Cardiovascular>>Platelet>>CD32/FCGR2

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD32/FCGR2

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Pathogen Recognition/Uptake>>CD32/FCGR2

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers>>CD32/FCGR2

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers>>CD32/FCGR2

Immunology>>Fc Receptor>>CD32/FCGR2

CD32 Related Products

Protein Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
CD16a/FCGR3A Human CD16a / FCGR3A Protein
CD16a/FCGR3A Human CD16a / FCGR3A Protein (176 Phe/Val)
CD16a/FCGR3A Human CD16a / FCGR3A Protein, with AVI Tag
CD16a/FCGR3A Human CD16a / FCGR3A Protein (176 Phe/Val), with AVI Tag
CD16/FCGR3 Mouse CD16 / FCGR3 Protein
CD16b/FCGR3B Human CD16b / FCGR2B Protein
CD16b/FCGR3B Human CD16b / FCGR3B Protein, Native
CD16-2/FCGR4 Mouse CD16-2 / FCGR4 Protein
CD89/FCAR Human CD89 / FCAR Protein
Antibody Products
Molecule Application Description //For Detailed Info. and Price------CLICK!
Human
CD16a/FCGR3A
WB  CD16a / FCGR3A Mouse MAb
Human CD16a/FCGR3A ELISA CD16a / FCGR3A Mouse MAb
Human
CD16a/FCGR3A
ELISA CD16a / FCGR3A Mouse MAb
Human
CD16b/FCGR3B
WB, ELISA CD16b / FCGR3B Rabbit PAb
Human
CD16b/FCGR3B
WB, ELISA CD16b / FCGR3B Rabbit PAb (Antigen Affinity Purified)
Mouse
CD16-2/FCGR4
WB, ELISA CD16-2 / FCGR4 Rabbit PAb
Mouse
CD16-2/FCGR4
WB, ELISA CD16-2 / FCGR4 Rabbit PAb (Antigen Affinity Purified)
cDNA Clone Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
CD16a/FCGR3A Human Homo sapiens CD16a / FCGR3A transcript variant 5 cDNA Clone(NM_001127596.1)
CD16a/FCGR3A Rat Rattus norvegicus CD16a / FCGR3A cDNA Clone
CD16-2/FCGR4 Mouse Mus musculus CD16-2 / FCGR4 cDNA Clone
CD32a/FCGR2A Human Homo sapiens CD32a / FCGR2A transcript variant 1 cDNA Clone(NM_001136219.1)
CD32b/FCGR2B Human Homo sapiens CD32b / FCGR2B transcript variant 3 cDNA Clone (NM_001002274.1)
CD32b/FCGR2B Human Homo sapiens CD32b / FCGR2B transcript variant 2 cDNA Clone (NM_001002273.1)
CD64/FCGR1 Human Homo sapiens CD64 / FCGR1 cDNA Clone(NM_000566.3)
CD64/FCGR1 Mouse Mus musculus CD64 / FCGR1 cDNA Clone
CD64/FCGR1 Rat Rattus norvegicus CD64 / FCGR1 cDNA Clone
CD89/FCAR Human Homo sapiens CD89 / FCAR transcript variant 1 cDNA Clone(NM_002000.2)
CD89/FCAR Rat Rattus norvegicus CD89 / FCAR cDNA Clone

CD32 Background

Receptors for Fc portion of IgG (Fcγ Rs) are members of the Ig superfamily, and are divided into three classes designated Fcγ RI (CD64), Fcγ RII (CD32), and Fcγ RIII (CD16). CD32 protein is a low affinity receptor for IgG that binds only IgG immune complexes and is expressed on a diverse range of cells such as monocytes, macrophages, neutrophils, eosinophils, platelets, and B cells. Human CD32 class is encoded by three closely related genes, and designated Fcγ RII A, B, and C which share 94-99% amino acid identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. CD32 is involved in a number of immune responses including antibody-dependent cell-mediated cytotoxicity, clearance of immune complexes, release of inflammatory mediators, and regulation of antibody production.

CD32 Related Studies

  1. Williams TE, et al. (2000) Concurrent and independent binding of Fcgamma receptors IIa and IIIb to surface-bound IgG. Biophys J. 79(4): 1867-75.
  2. Kanters D, et al. (2007) Expression of activated Fc gamma RII discriminates between multiple granulocyte-priming phenotypes in peripheral blood of allergic asthmatic subjects. J Allergy Clin Immunol. 120(5): 1073-81.
  3. Veri MC, et al. (2007) Monoclonal antibodies capable of discriminating the human inhibitory Fcgamma-receptor IIB (CD32B) from the activating Fcgamma-receptor IIA (CD32A): biochemical, biological and functional characterization. Immunology. 121(3): 392-404.

 

 

CD32 (FCGR, Fc gamma Receptor) related areas, pathways, and other information